Humoral response 24 months after the first COVID-19 vaccination in people with HIV with and without diabetes

Louise Bering, Line Dam Heftdal, Safura Luise Heidari, Sebastian Rask Hamm, Cecillie Bo Hansen, Dina Leth Møller, Mia Pries-Heje, Kamille Fogh, Rasmus Bo Hasselbalch, Laura Pérez-Alós, Jan Gerstoft, Thomas Benfield, Selina Kikkenborg Berg, Anne Vinggaard Christensen, Nina Marie Birk, Linda Maria Hilsted, Sisse Rye Ostrowski, Ruth Frikke-Schmidt, Erik Sørensen, Kirsten GrønbækHenning Bundgaard, Kasper Iversen, Peter Garred, Susanne Dam Nielsen*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

People with HIV (PWH) and people with diabetes mellitus have increased risk of severe COVID-19, but little is known about humoral response to COVID-19 vaccines in PWH with DM. We investigated SARS-CoV-2 antireceptor-binding domain (anti-RBD) immunoglobulin G (IgG) geometrical concentrations and neutralizing antibody capacity (nAB) in PWH with and without diabetes mellitus. Anti-RBD IgG and nAB in COVID-19-vaccinated PWH were not associated with diabetes mellitus-status or HbA1c 24 months after the initial COVID-19 vaccination.

Original languageEnglish
JournalAIDS
Volume38
Issue number15
Pages (from-to)2100-2103
Number of pages4
ISSN0269-9370
DOIs
Publication statusPublished - 2024

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