Hyperspectral imaging as a part of pharmaceutical product design

Johan Bøtker, Jian X. Wu, Jukka Rantanen*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

15 Citations (Scopus)

Abstract

Imaging is getting an important element of the modern drug development process. Different hyperspectral imaging tools can provide in-depth understanding of complex pharmaceutical products including not only phenomena captured by the laboratory-based off-line instruments but also increasingly tools capable of fulfilling the process analytical measurement scenarios. Information related to spatial distribution of the components in pharmaceutical products can be explored using infrared, near-infrared, Raman, and ultraviolet mapping, as well as using RGB imaging. These tools are generally accepted by the regulatory bodies, and at the same time, they are becoming a natural part of drug development process. In the future, hyperspectral imaging will be a key enabling part of the continuously operating production systems.

Original languageEnglish
Title of host publicationData Handling in Science and Technology
Number of pages15
PublisherElsevier
Publication date2020
Pages567-581
DOIs
Publication statusPublished - 2020
SeriesData Handling in Science and Technology
Volume32
ISSN0922-3487

Keywords

  • Chemical imaging
  • Near-IR (NIR) imaging
  • Pharmaceutical
  • Raman imaging
  • Tablets

Cite this