Identification of CD8+ T cell epitopes in the West Nile virus polyprotein by reverse-immunology using NetCTL

Mette Voldby Larsen; Alina Lelic; Robin Parsons; Morten Nielsen; Ilka Hoof; Kasper Lamberth; Mark B Loeb; Søren Buus; Jonathan Bramson; Ole Lund

doi:10.1371/journal.pone.0012697

Identification of CD8+ T cell epitopes in the West Nile virus polyprotein by reverse-immunology using NetCTL

Mette Voldby Larsen, Alina Lelic, Robin Parsons, Morten Nielsen, Ilka Hoof, Kasper Lamberth, Mark B Loeb, Søren Buus, Jonathan Bramson, Ole Lund

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

Abstract

West Nile virus (WNV) is a growing threat to public health and a greater understanding of the immune response raised against WNV is important for the development of prophylactic and therapeutic strategies.

Original language	English
Journal	P L o S One
Volume	5
Issue number	9
Pages (from-to)	e12697
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0012697
Publication status	Published - 1 Jan 2010

Keywords

Adult
Aged
Amino Acid Sequence
Antigens, CD8
Cohort Studies
Computational Biology
Epitope Mapping
Epitopes, T-Lymphocyte
Female
Humans
Male
Middle Aged
Molecular Sequence Data
Polyproteins
T-Lymphocytes, Cytotoxic
West Nile Fever
West Nile virus

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Cite this

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title = "Identification of CD8+ T cell epitopes in the West Nile virus polyprotein by reverse-immunology using NetCTL",

abstract = "West Nile virus (WNV) is a growing threat to public health and a greater understanding of the immune response raised against WNV is important for the development of prophylactic and therapeutic strategies.",

keywords = "Adult, Aged, Amino Acid Sequence, Antigens, CD8, Cohort Studies, Computational Biology, Epitope Mapping, Epitopes, T-Lymphocyte, Female, Humans, Male, Middle Aged, Molecular Sequence Data, Polyproteins, T-Lymphocytes, Cytotoxic, West Nile Fever, West Nile virus",

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T1 - Identification of CD8+ T cell epitopes in the West Nile virus polyprotein by reverse-immunology using NetCTL

AU - Larsen, Mette Voldby

AU - Lelic, Alina

AU - Parsons, Robin

AU - Nielsen, Morten

AU - Hoof, Ilka

AU - Lamberth, Kasper

AU - Loeb, Mark B

AU - Buus, Søren

AU - Bramson, Jonathan

AU - Lund, Ole

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N2 - West Nile virus (WNV) is a growing threat to public health and a greater understanding of the immune response raised against WNV is important for the development of prophylactic and therapeutic strategies.

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KW - Aged

KW - Amino Acid Sequence

KW - Antigens, CD8

KW - Cohort Studies

KW - Computational Biology

KW - Epitope Mapping

KW - Epitopes, T-Lymphocyte

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Molecular Sequence Data

KW - Polyproteins

KW - T-Lymphocytes, Cytotoxic

KW - West Nile Fever

KW - West Nile virus

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