Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review

Cordula Stillhart; Katarina Vucicevic; Patrick Augustijns; Abdul W. Basit; Hannah Batchelor; Talia R. Flanagan; Ina Gesquiere; Rick Greupink; Daniel Keszthelyi; Mikko Koskinen; Christine M. Madla; Christophe Matthys; Goran Miljus; Miriam G. Mooij; Neil Parrott; Anna -Lena Ungell; Saskia N. de Wildt; Mine Orlu; Sandra Klein; Anette Mullertz

doi:10.1016/j.ejps.2020.105280

Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review

Cordula Stillhart, Katarina Vucicevic, Patrick Augustijns, Abdul W. Basit, Hannah Batchelor, Talia R. Flanagan, Ina Gesquiere, Rick Greupink, Daniel Keszthelyi, Mikko Koskinen, Christine M. Madla, Christophe Matthys, Goran Miljus, Miriam G. Mooij, Neil Parrott, Anna -Lena Ungell, Saskia N. de Wildt, Mine Orlu, Sandra Klein, Anette Mullertz^*

^*Corresponding author for this work

Physiological Pharmaceutics

Research output: Contribution to journal › Review › Research › peer-review

168 Citations (Scopus)

115 Downloads (Pure)

Original language	English
Article number	105280
Journal	European Journal of Pharmaceutical Sciences
Volume	147
Number of pages	28
ISSN	0928-0987
DOIs	https://doi.org/10.1016/j.ejps.2020.105280
Publication status	Published - 2020

Keywords

HELICOBACTER-PYLORI INFECTION
SMALL-INTESTINAL TRANSIT
INFLAMMATORY-BOWEL-DISEASE
GASTRIC BYPASS-SURGERY
BINDING CASSETTE TRANSPORTERS
MESSENGER-RNA EXPRESSION
VIDEO CAPSULE ENDOSCOPY
ASCENDING COLON FLUIDS
IN-VIVO PERFORMANCE
CANCER CELL-LINES

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Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP reviewFinal published version, 4.15 MBLicence: CC BY

Cite this

Stillhart, C., Vucicevic, K., Augustijns, P., Basit, A. W., Batchelor, H., Flanagan, T. R., Gesquiere, I., Greupink, R., Keszthelyi, D., Koskinen, M., Madla, C. M., Matthys, C., Miljus, G., Mooij, M. G., Parrott, N., Ungell, A. -L., de Wildt, S. N., Orlu, M., Klein, S., & Mullertz, A. (2020). Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review. European Journal of Pharmaceutical Sciences, 147, [105280]. https://doi.org/10.1016/j.ejps.2020.105280

Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review. / Stillhart, Cordula; Vucicevic, Katarina; Augustijns, Patrick; Basit, Abdul W.; Batchelor, Hannah; Flanagan, Talia R.; Gesquiere, Ina; Greupink, Rick; Keszthelyi, Daniel; Koskinen, Mikko; Madla, Christine M.; Matthys, Christophe; Miljus, Goran; Mooij, Miriam G.; Parrott, Neil; Ungell, Anna -Lena; de Wildt, Saskia N.; Orlu, Mine; Klein, Sandra; Mullertz, Anette.

In: European Journal of Pharmaceutical Sciences, Vol. 147, 105280, 2020.

Research output: Contribution to journal › Review › Research › peer-review

Stillhart, C, Vucicevic, K, Augustijns, P, Basit, AW, Batchelor, H, Flanagan, TR, Gesquiere, I, Greupink, R, Keszthelyi, D, Koskinen, M, Madla, CM, Matthys, C, Miljus, G, Mooij, MG, Parrott, N, Ungell, A-L, de Wildt, SN, Orlu, M, Klein, S & Mullertz, A 2020, 'Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review', European Journal of Pharmaceutical Sciences, vol. 147, 105280. https://doi.org/10.1016/j.ejps.2020.105280

Stillhart, Cordula ; Vucicevic, Katarina ; Augustijns, Patrick ; Basit, Abdul W. ; Batchelor, Hannah ; Flanagan, Talia R. ; Gesquiere, Ina ; Greupink, Rick ; Keszthelyi, Daniel ; Koskinen, Mikko ; Madla, Christine M. ; Matthys, Christophe ; Miljus, Goran ; Mooij, Miriam G. ; Parrott, Neil ; Ungell, Anna -Lena ; de Wildt, Saskia N. ; Orlu, Mine ; Klein, Sandra ; Mullertz, Anette. / Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review. In: European Journal of Pharmaceutical Sciences. 2020 ; Vol. 147.

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title = "Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review",

keywords = "HELICOBACTER-PYLORI INFECTION, SMALL-INTESTINAL TRANSIT, INFLAMMATORY-BOWEL-DISEASE, GASTRIC BYPASS-SURGERY, BINDING CASSETTE TRANSPORTERS, MESSENGER-RNA EXPRESSION, VIDEO CAPSULE ENDOSCOPY, ASCENDING COLON FLUIDS, IN-VIVO PERFORMANCE, CANCER CELL-LINES",

author = "Cordula Stillhart and Katarina Vucicevic and Patrick Augustijns and Basit, {Abdul W.} and Hannah Batchelor and Flanagan, {Talia R.} and Ina Gesquiere and Rick Greupink and Daniel Keszthelyi and Mikko Koskinen and Madla, {Christine M.} and Christophe Matthys and Goran Miljus and Mooij, {Miriam G.} and Neil Parrott and Ungell, {Anna -Lena} and {de Wildt}, {Saskia N.} and Mine Orlu and Sandra Klein and Anette Mullertz",

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AU - Batchelor, Hannah

AU - Flanagan, Talia R.

AU - Gesquiere, Ina

AU - Greupink, Rick

AU - Keszthelyi, Daniel

AU - Koskinen, Mikko

AU - Madla, Christine M.

AU - Matthys, Christophe

AU - Miljus, Goran

AU - Mooij, Miriam G.

AU - Parrott, Neil

AU - Ungell, Anna -Lena

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AU - Klein, Sandra

AU - Mullertz, Anette

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KW - INFLAMMATORY-BOWEL-DISEASE

KW - GASTRIC BYPASS-SURGERY

KW - BINDING CASSETTE TRANSPORTERS

KW - MESSENGER-RNA EXPRESSION

KW - VIDEO CAPSULE ENDOSCOPY

KW - ASCENDING COLON FLUIDS

KW - IN-VIVO PERFORMANCE

KW - CANCER CELL-LINES

U2 - 10.1016/j.ejps.2020.105280

DO - 10.1016/j.ejps.2020.105280

M3 - Review

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JO - Norvegica Pharmaceutica Acta

JF - Norvegica Pharmaceutica Acta

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