Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

Philip L S M Gordts; Alexander Bartelt; Stefan K Nilsson; Wim Annaert; Christina Christoffersen; Lars Bo Nielsen; Joerg Heeren; Anton J M Roebroek

doi:10.1371/journal.pone.0038330

Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

Philip L S M Gordts, Alexander Bartelt, Stefan K Nilsson, Wim Annaert, Christina Christoffersen, Lars Bo Nielsen, Joerg Heeren, Anton J M Roebroek

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

Abstract

Determination of the in vivo significance of LDL receptor-related protein 1 (LRP1) dysfunction on lipid metabolism and atherosclerosis development in absence of its main ligand apoE.

Original language	English
Journal	P L o S One
Volume	7
Issue number	6
Pages (from-to)	e38330
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0038330
Publication status	Published - 2012

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title = "Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice",

abstract = "Determination of the in vivo significance of LDL receptor-related protein 1 (LRP1) dysfunction on lipid metabolism and atherosclerosis development in absence of its main ligand apoE.",

author = "Gordts, {Philip L S M} and Alexander Bartelt and Nilsson, {Stefan K} and Wim Annaert and Christina Christoffersen and Nielsen, {Lars Bo} and Joerg Heeren and Roebroek, {Anton J M}",

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doi = "10.1371/journal.pone.0038330",

language = "English",

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T1 - Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

AU - Gordts, Philip L S M

AU - Bartelt, Alexander

AU - Nilsson, Stefan K

AU - Annaert, Wim

AU - Christoffersen, Christina

AU - Nielsen, Lars Bo

AU - Heeren, Joerg

AU - Roebroek, Anton J M

PY - 2012

Y1 - 2012

N2 - Determination of the in vivo significance of LDL receptor-related protein 1 (LRP1) dysfunction on lipid metabolism and atherosclerosis development in absence of its main ligand apoE.

AB - Determination of the in vivo significance of LDL receptor-related protein 1 (LRP1) dysfunction on lipid metabolism and atherosclerosis development in absence of its main ligand apoE.

U2 - 10.1371/journal.pone.0038330

DO - 10.1371/journal.pone.0038330

M3 - Journal article

C2 - 22701627

SN - 1932-6203

VL - 7

SP - e38330

JO - P L o S One

JF - P L o S One

IS - 6

ER -