Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

Eugeni Belda; Lise Voland; Valentina Tremaroli; Gwen Falony; Solia Adriouch; Karen E. Assmann; Edi Prifiti; Judith Aron-Wisnewsky; Jean Debedat; Tiphaine Le Roy; Trine Nielsen; Chloe Amouyal; Sebastien Andre; Fabrizio Andreelli; Matthias Blueher; Rima Chakaroun; Julien Chilloux; Luis Pedro Coelho; Maria Carlota Dao; Promi Das; Soraya Fellahi; Sofia Forslund; Nathalie Galleron; Tue H. Hansen; Bridget Holmes; Boyang Ji; Helle Krogh Pedersen; null Phuong Le; Emmanuelle Le Chatelier; Christian Lewinter; Louise Manneras-Holm; Florian Marquet; Antonis Myridakis; Veronique Pelloux; Nicolas Pons; Benoit Quinquis; Christine Rouault; Hugo Roume; Joe-Elie Salem; Nataliya Sokolovska; Nadja B. Søndertoft; Sothea Touch; Sara Vieira-Silva; Pilar Galan; Jens Holst; Jens Peter Gøtze; Lars Køber; Henrik Vestergaard; Torben Hansen; Serge Hercberg; Jean-Michel Oppert; Jens Nielsen; Ivica Letunic; Marc-Emmanuel Dumas; Michael Stumvoll; Oluf Borbye Pedersen; Peer Bork; Stanislav Dusko Ehrlich; Jean-Daniel Zucker; Fredrik Baeckhed; Jeroen Raes; Karine Clement

doi:10.1136/gutjnl-2021-325753

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

Eugeni Belda, Lise Voland, Valentina Tremaroli, Gwen Falony, Solia Adriouch, Karen E. Assmann, Edi Prifiti, Judith Aron-Wisnewsky, Jean Debedat, Tiphaine Le Roy, Trine Nielsen, Chloe Amouyal, Sebastien Andre, Fabrizio Andreelli, Matthias Blueher, Rima Chakaroun, Julien Chilloux, Luis Pedro Coelho, Maria Carlota Dao, Promi DasSoraya Fellahi, Sofia Forslund, Nathalie Galleron, Tue H. Hansen, Bridget Holmes, Boyang Ji, Helle Krogh Pedersen, Phuong Le, Emmanuelle Le Chatelier, Christian Lewinter, Louise Manneras-Holm, Florian Marquet, Antonis Myridakis, Veronique Pelloux, Nicolas Pons, Benoit Quinquis, Christine Rouault, Hugo Roume, Joe-Elie Salem, Nataliya Sokolovska, Nadja B. Søndertoft, Sothea Touch, Sara Vieira-Silva, Pilar Galan, Jens Holst, Jens Peter Gøtze, Lars Køber, Henrik Vestergaard, Torben Hansen, Serge Hercberg, Jean-Michel Oppert, Jens Nielsen, Ivica Letunic, Marc-Emmanuel Dumas, Michael Stumvoll, Oluf Borbye Pedersen, Peer Bork, Stanislav Dusko Ehrlich, Jean-Daniel Zucker, Fredrik Baeckhed, Jeroen Raes, Karine Clement

Research output: Contribution to journal › Journal article › Research › peer-review

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Original language	English
Journal	Gut
Volume	71
Issue number	12
Pages (from-to)	2463-2480
Number of pages	18
ISSN	0017-5749
DOIs	https://doi.org/10.1136/gutjnl-2021-325753
Publication status	Published - 2022

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Belda, E., Voland, L., Tremaroli, V., Falony, G., Adriouch, S., Assmann, K. E., Prifiti, E., Aron-Wisnewsky, J., Debedat, J., Le Roy, T., Nielsen, T., Amouyal, C., Andre, S., Andreelli, F., Blueher, M., Chakaroun, R., Chilloux, J., Coelho, L. P., Dao, M. C., ... Clement, K. (2022). Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism. Gut, 71(12), 2463-2480. https://doi.org/10.1136/gutjnl-2021-325753

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity : effect of biotin and prebiotic supplementation on improved metabolism. / Belda, Eugeni; Voland, Lise; Tremaroli, Valentina; Falony, Gwen; Adriouch, Solia; Assmann, Karen E.; Prifiti, Edi; Aron-Wisnewsky, Judith; Debedat, Jean; Le Roy, Tiphaine; Nielsen, Trine; Amouyal, Chloe; Andre, Sebastien; Andreelli, Fabrizio; Blueher, Matthias; Chakaroun, Rima; Chilloux, Julien; Coelho, Luis Pedro; Dao, Maria Carlota; Das, Promi; Fellahi, Soraya; Forslund, Sofia; Galleron, Nathalie; Hansen, Tue H.; Holmes, Bridget; Ji, Boyang; Pedersen, Helle Krogh; Phuong Le; Le Chatelier, Emmanuelle; Lewinter, Christian; Manneras-Holm, Louise; Marquet, Florian; Myridakis, Antonis; Pelloux, Veronique; Pons, Nicolas; Quinquis, Benoit; Rouault, Christine; Roume, Hugo; Salem, Joe-Elie; Sokolovska, Nataliya; Søndertoft, Nadja B.; Touch, Sothea; Vieira-Silva, Sara; Galan, Pilar; Holst, Jens; Gøtze, Jens Peter; Køber, Lars ; Vestergaard, Henrik ; Hansen, Torben; Hercberg, Serge; Oppert, Jean-Michel; Nielsen, Jens; Letunic, Ivica; Dumas, Marc-Emmanuel; Stumvoll, Michael; Pedersen, Oluf Borbye; Bork, Peer; Ehrlich, Stanislav Dusko; Zucker, Jean-Daniel; Baeckhed, Fredrik; Raes, Jeroen; Clement, Karine.

In: Gut, Vol. 71, No. 12, 2022, p. 2463-2480.

Research output: Contribution to journal › Journal article › Research › peer-review

Belda, E, Voland, L, Tremaroli, V, Falony, G, Adriouch, S, Assmann, KE, Prifiti, E, Aron-Wisnewsky, J, Debedat, J, Le Roy, T, Nielsen, T, Amouyal, C, Andre, S, Andreelli, F, Blueher, M, Chakaroun, R, Chilloux, J, Coelho, LP, Dao, MC, Das, P, Fellahi, S, Forslund, S, Galleron, N, Hansen, TH, Holmes, B, Ji, B, Pedersen, HK, Phuong Le, Le Chatelier, E, Lewinter, C, Manneras-Holm, L, Marquet, F, Myridakis, A, Pelloux, V, Pons, N, Quinquis, B, Rouault, C, Roume, H, Salem, J-E, Sokolovska, N, Søndertoft, NB, Touch, S, Vieira-Silva, S, Galan, P, Holst, J, Gøtze, JP, Køber, L , Vestergaard, H , Hansen, T, Hercberg, S, Oppert, J-M, Nielsen, J, Letunic, I, Dumas, M-E, Stumvoll, M, Pedersen, OB, Bork, P, Ehrlich, SD, Zucker, J-D, Baeckhed, F, Raes, J & Clement, K 2022, 'Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism', Gut, vol. 71, no. 12, pp. 2463-2480. https://doi.org/10.1136/gutjnl-2021-325753

Belda, Eugeni ; Voland, Lise ; Tremaroli, Valentina ; Falony, Gwen ; Adriouch, Solia ; Assmann, Karen E. ; Prifiti, Edi ; Aron-Wisnewsky, Judith ; Debedat, Jean ; Le Roy, Tiphaine ; Nielsen, Trine ; Amouyal, Chloe ; Andre, Sebastien ; Andreelli, Fabrizio ; Blueher, Matthias ; Chakaroun, Rima ; Chilloux, Julien ; Coelho, Luis Pedro ; Dao, Maria Carlota ; Das, Promi ; Fellahi, Soraya ; Forslund, Sofia ; Galleron, Nathalie ; Hansen, Tue H. ; Holmes, Bridget ; Ji, Boyang ; Pedersen, Helle Krogh ; Phuong Le ; Le Chatelier, Emmanuelle ; Lewinter, Christian ; Manneras-Holm, Louise ; Marquet, Florian ; Myridakis, Antonis ; Pelloux, Veronique ; Pons, Nicolas ; Quinquis, Benoit ; Rouault, Christine ; Roume, Hugo ; Salem, Joe-Elie ; Sokolovska, Nataliya ; Søndertoft, Nadja B. ; Touch, Sothea ; Vieira-Silva, Sara ; Galan, Pilar ; Holst, Jens ; Gøtze, Jens Peter ; Køber, Lars ; Vestergaard, Henrik ; Hansen, Torben ; Hercberg, Serge ; Oppert, Jean-Michel ; Nielsen, Jens ; Letunic, Ivica ; Dumas, Marc-Emmanuel ; Stumvoll, Michael ; Pedersen, Oluf Borbye ; Bork, Peer ; Ehrlich, Stanislav Dusko ; Zucker, Jean-Daniel ; Baeckhed, Fredrik ; Raes, Jeroen ; Clement, Karine. / Impairment of gut microbial biotin metabolism and host biotin status in severe obesity : effect of biotin and prebiotic supplementation on improved metabolism. In: Gut. 2022 ; Vol. 71, No. 12. pp. 2463-2480.

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AU - Falony, Gwen

AU - Adriouch, Solia

AU - Assmann, Karen E.

AU - Prifiti, Edi

AU - Aron-Wisnewsky, Judith

AU - Debedat, Jean

AU - Le Roy, Tiphaine

AU - Nielsen, Trine

AU - Amouyal, Chloe

AU - Andre, Sebastien

AU - Andreelli, Fabrizio

AU - Blueher, Matthias

AU - Chakaroun, Rima

AU - Chilloux, Julien

AU - Coelho, Luis Pedro

AU - Dao, Maria Carlota

AU - Das, Promi

AU - Fellahi, Soraya

AU - Forslund, Sofia

AU - Galleron, Nathalie

AU - Hansen, Tue H.

AU - Holmes, Bridget

AU - Ji, Boyang

AU - Pedersen, Helle Krogh

AU - Phuong Le, null

AU - Le Chatelier, Emmanuelle

AU - Lewinter, Christian

AU - Manneras-Holm, Louise

AU - Marquet, Florian

AU - Myridakis, Antonis

AU - Pelloux, Veronique

AU - Pons, Nicolas

AU - Quinquis, Benoit

AU - Rouault, Christine

AU - Roume, Hugo

AU - Salem, Joe-Elie

AU - Sokolovska, Nataliya

AU - Søndertoft, Nadja B.

AU - Touch, Sothea

AU - Vieira-Silva, Sara

AU - Galan, Pilar

AU - Holst, Jens

AU - Gøtze, Jens Peter

AU - Køber, Lars

AU - Vestergaard, Henrik

AU - Hansen, Torben

AU - Hercberg, Serge

AU - Oppert, Jean-Michel

AU - Nielsen, Jens

AU - Letunic, Ivica

AU - Dumas, Marc-Emmanuel

AU - Stumvoll, Michael

AU - Pedersen, Oluf Borbye

AU - Bork, Peer

AU - Ehrlich, Stanislav Dusko

AU - Zucker, Jean-Daniel

AU - Baeckhed, Fredrik

AU - Raes, Jeroen

AU - Clement, Karine

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DO - 10.1136/gutjnl-2021-325753

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JO - Gut

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