Improved glucose tolerance after intensive life style intervention occurs without changes in muscle ceramide or triacylglycerol in morbidly obese subjects

Jørn Wulff Helge, Bente Merete Stallknecht, Tue Drachmann, Lars Hellgren, R Jiménez-Jiménez, J L Andersen, Bjørn Richelsen, J M Bruun

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Abstract

This study investigated the effect of a 15-week life style intervention (hypocaloric diet and regular exercise) on glucose tolerance, skeletal muscle lipids and muscle metabolic adaptations in 14 female and 9 male morbidly obese subjects (age: 32.5±2.3 years, body mass index: 46.1±1.9 kg m(-2) ).
Original languageEnglish
JournalActa Physiologica (Print)
Volume201
Issue number3
Pages (from-to)357-64
Number of pages8
ISSN1748-1708
DOIs
Publication statusPublished - 1 Mar 2011

Keywords

  • Adult
  • Ceramides
  • Diet Therapy
  • Exercise Therapy
  • Female
  • Glucose
  • Glucose Tolerance Test
  • Humans
  • Life Style
  • Male
  • Muscle, Skeletal
  • Obesity, Morbid
  • Treatment Outcome
  • Triglycerides
  • Young Adult

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