Abstract
Rodent studies have indicated that low-carbohydrate diets prevent age-related cognitive decline and extend lifespan due to increased circulating levels of ketone bodies. A possible physiological mechanism for how ketone bodies exert this effect might be by improving central nervous system insulin resistance, which makes this finding interesting with regards to the prevention of cognitive decline and dementia in patients with type 2 diabetes mellitus.
Original language | English |
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Journal | Nature Reviews Endocrinology |
Volume | 13 |
Issue number | 12 |
Pages (from-to) | 695-696 |
Number of pages | 2 |
ISSN | 1759-5029 |
DOIs | |
Publication status | Published - 2017 |
Keywords
- Ageing