Induction of systemic zygomycosis in pregnant mice by Absidia corymbifera

H. E. Jensen*, B. Aalbaek, J. Hau

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

5 Citations (Scopus)

Abstract

Intravenous inoculation of pregnant BALB/c mice with 103 to 105 Absidia corymbifera spores resulted in mycotic placentitis when 104 or more spores were given. Compared with challenge on day 10, challenge on days 12 and 14 of pregnancy resulted in significantly more placentas being infected. Placentitis was seen in 2.4 to 6.7% of the placentas from animals given 104 spores on days 12 and 14 respectively, compared with 14.0 and 15.2% of the placentas in animals challenged on the same days with 105 spores. Absidia corymbifera did not have particular affinity for placental localization because extrauterine organs were also frequently.

Original languageEnglish
JournalLaboratory Animal Science
Volume45
Issue number3
Pages (from-to)254-257
Number of pages4
ISSN0023-6764
Publication statusPublished - 1995

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