Infrared neural stimulation and electrophysiology in a soft fiber-based neural interface

Marcello Meneghetti; Kunyang Sui; Jaspreet Kaur; Roar Jakob Fleng  Sørensen; Rune W. Berg; Christos Markos

doi:10.1117/12.2646177

Infrared neural stimulation and electrophysiology in a soft fiber-based neural interface

Marcello Meneghetti, Kunyang Sui, Jaspreet Kaur, Roar Jakob Fleng Sørensen, Rune W. Berg, Christos Markos^*

^*Corresponding author for this work

Neuronal Signalling

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Abstract

Infrared neurostimulation has emerged in recent years as a promising technique for controlling neuronal activity without genetic manipulation. Having high absorption of the employed wavelengths as its fundamental mechanism, it requires implantable platforms to deliver light in brain regions deeper than the first cortical layers. Due to the spatial confinement of the stimulation, electrodes integrated in close proximity to the illumination spot are desirable to verify the effects of the stimulation by extracellular electrophysiology. Here we developed and validated in vivo a multifunctional neural interface based on a soft, biocompatible polymer optical fiber that allows simultaneous infrared neurostimulation and electrophysiology.

Original language	English
Title of host publication	Optogenetics and Optical Manipulation 2023 : Proceedings
Number of pages	6
Volume	12366
Publisher	SPIE--The International Society for Optical Engineering
Publication date	2023
Pages	13-18
Article number	1236605
Chapter	5
DOIs	https://doi.org/10.1117/12.2646177
Publication status	Published - 2023
Event	Optogenetics and Optical Manipulation 2023 - San Francisco, United States Duration: 28 Jan 2023 → 3 Feb 2023 https://spie.org/Publications/Proceedings/Volume/PC12366

Conference

Conference	Optogenetics and Optical Manipulation 2023
Country/Territory	United States
City	San Francisco
Period	28/01/2023 → 03/02/2023
Internet address	https://spie.org/Publications/Proceedings/Volume/PC12366

Access to Document

10.1117/12.2646177

FulltextFinal published version, 3.09 MB

Cite this

Infrared neural stimulation and electrophysiology in a soft fiber-based neural interface. / Meneghetti, Marcello ; Sui, Kunyang ; Kaur, Jaspreet; Sørensen, Roar Jakob Fleng ; Berg, Rune W.; Markos, Christos.

Optogenetics and Optical Manipulation 2023: Proceedings. Vol. 12366 SPIE--The International Society for Optical Engineering, 2023. p. 13-18 1236605.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Meneghetti, M , Sui, K , Kaur, J, Sørensen, RJF, Berg, RW & Markos, C 2023, Infrared neural stimulation and electrophysiology in a soft fiber-based neural interface. in Optogenetics and Optical Manipulation 2023: Proceedings. vol. 12366, 1236605, SPIE--The International Society for Optical Engineering, pp. 13-18, Optogenetics and Optical Manipulation 2023, San Francisco, California, United States, 28/01/2023. https://doi.org/10.1117/12.2646177

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