Intraoperative platelet and plasma improves survival in patients operated for a rAAA: a follow-up evaluation

Per Ingemar Johansson, F. Swiatek, L. Jorgensen, Leif Pandora Jensen, N.H. Secher

Research output: Contribution to journalJournal articleResearchpeer-review

16 Citations (Scopus)

Abstract

OBJECTIVES: Continued haemorrhage remains a significant contributor to mortality in massively transfused patients. We found that early administration of platelets and plasma reduced mortality from 54% to 36% in rAAA patients. The aim of the present evaluation was to evaluate whether reduced mortality in rAAA patients related to a pro-active transfusion therapy is maintained. DESIGN: Single-centre observational study. METHODS: Mortality of patients operated for rAAA 2006-07 was compared to that of patients operated 2004-05 (intervention group; n=50) and 2002-04 (control group, n=82). RESULTS: 64 consecutive patients with rAAA received, similar to the intervention group, more platelets (5 and 4 vs. 0 units, P<0.05) and plasma (12 and 11 vs. 7 units, P<0.05) intraoperatively and had a higher platelet count (158 and 155 vs. 69 x 10(9)/L, P<0.0001) upon arrival at the intensive care unit and the 30-day mortality remained reduced (24% and 36% vs. 56%, P<0.01 and P=0.02, respectively) as compared to the control patients. CONCLUSIONS: Early administration of platelets and plasma, together with red blood cells maintained reduced mortality in patients operated for rAAAin a 18 month period
Udgivelsesdato: 2008/10
Original languageEnglish
JournalEuropean Journal of Vascular and Endovascular Surgery
Volume36
Issue number4
Pages (from-to)397-400
Number of pages3
ISSN1078-5884
Publication statusPublished - 2008

Cite this