"Live high-train low" using normobaric hypoxia: a double-blinded, placebo-controlled study

Christoph Siebenmann; Paul Robach; Robert A Jacobs; Peter Rasmussen; Nikolai Nordsborg; Victor Diaz; Andreas Christ; Niels Vidiendal Olsen; Marco Maggiorini; Carsten Lundby

doi:10.1152/japplphysiol.00388.2011

"Live high-train low" using normobaric hypoxia: a double-blinded, placebo-controlled study

Christoph Siebenmann, Paul Robach, Robert A Jacobs, Peter Rasmussen, Nikolai Nordsborg, Victor Diaz, Andreas Christ, Niels Vidiendal Olsen, Marco Maggiorini, Carsten Lundby

Research output: Contribution to journal › Journal article › Research › peer-review

135 Citations (Scopus)

Abstract

The combination of living at altitude and training near sea level [live high-train low (LHTL)] may improve performance of endurance athletes. However, to date, no study can rule out a potential placebo effect as at least part of the explanation, especially for performance measures. With the use of a placebo-controlled, double-blinded design, we tested the hypothesis that LHTL-related improvements in endurance performance are mediated through physiological mechanisms and not through a placebo effect. Sixteen endurance cyclists trained for 8 wk at low altitude (

Original language	English
Journal	Journal of Applied Physiology
Volume	112
Issue number	1
Pages (from-to)	106-117
Number of pages	12
ISSN	8750-7587
DOIs	https://doi.org/10.1152/japplphysiol.00388.2011
Publication status	Published - 2012

Access to Document

10.1152/japplphysiol.00388.2011

Cite this

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abstract = "The combination of living at altitude and training near sea level [live high-train low (LHTL)] may improve performance of endurance athletes. However, to date, no study can rule out a potential placebo effect as at least part of the explanation, especially for performance measures. With the use of a placebo-controlled, double-blinded design, we tested the hypothesis that LHTL-related improvements in endurance performance are mediated through physiological mechanisms and not through a placebo effect. Sixteen endurance cyclists trained for 8 wk at low altitude (",

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AU - Robach, Paul

AU - Jacobs, Robert A

AU - Rasmussen, Peter

AU - Nordsborg, Nikolai

AU - Diaz, Victor

AU - Christ, Andreas

AU - Olsen, Niels Vidiendal

AU - Maggiorini, Marco

AU - Lundby, Carsten

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AB - The combination of living at altitude and training near sea level [live high-train low (LHTL)] may improve performance of endurance athletes. However, to date, no study can rule out a potential placebo effect as at least part of the explanation, especially for performance measures. With the use of a placebo-controlled, double-blinded design, we tested the hypothesis that LHTL-related improvements in endurance performance are mediated through physiological mechanisms and not through a placebo effect. Sixteen endurance cyclists trained for 8 wk at low altitude (

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