Long-term follow-up of patients with contained annulus ruptures after TAVI: the EuropeaN COntained RupturE (ENCORE) registry

Philipp Breitbart, Jan Minners, Gregor Pache, Nicolaj Christopher Hansson, Bjarne Linde Nørgaard, Ole De Backer, Lars Søndergaard, Osama Alsanjari, David Hildick-Smith, Mohamed Abdel-Wahab, Stephanie Löbig, Franz-Josef Neumann, Philipp Ruile

Research output: Contribution to journalJournal articleResearchpeer-review

5 Citations (Scopus)

Abstract

AIMS: The purpose of this registry was to determine the long-term outcomes in patients with asymptomatic contained annulus rupture (CR) as a rare complication of transcatheter aortic valve implantation (TAVI).

METHODS AND RESULTS: The ENCORE registry is a multicentre registry (six centres across Europe) of patients with CR diagnosed on post-TAVI computed tomography angiography (CTA) or transoesophageal echocardiography (TEE). A total of 21 patients (mean age 81.9±4.1 years, 81% balloon-expandable TAVI prostheses) were diagnosed with CR (mean size of lesions was 15.3±6.9 × 8.5±3.3 × 8.5±2.3 mm). Seventeen were diagnosed among a total of 1,602 consecutive routine post-TAVI CTA (incidence 1.1%), two in TEE and two in post-TAVI CTA (each conducted due to suspicion of peri-interventional complications). During a mean follow-up of 2.3±1.7 years (cumulative 48.6 patient-years), nine patients (43%) died from non-cardiac causes. None of the patients exhibited symptoms or underwent interventional treatment related to the CR; no sudden cardiac death occurred. A follow-up CTA, performed in eleven patients 240±176 days post TAVI, revealed stable CR findings in seven, regression in one, and remission in three patients.

CONCLUSIONS: The results of our international multicentre registry demonstrate favourable long-term outcomes of CR after TAVI supporting a watch-and-wait strategy in these patients.

Original languageEnglish
JournalEuroIntervention
Volume16
Issue number1
Pages (from-to)83-88
ISSN1774-024X
DOIs
Publication statusPublished - 2020

Keywords

  • Aged
  • Aged, 80 and over
  • Aortic Valve
  • Aortic Valve Stenosis
  • Europe
  • Follow-Up Studies
  • Heart Valve Prosthesis
  • Heart Valve Prosthesis Implantation
  • Humans
  • Longitudinal Studies
  • Registries
  • Time Factors
  • Transcatheter Aortic Valve Replacement/adverse effects
  • Treatment Outcome

Cite this