Abstract
It is unknown if long-term remission for pediatric obsessive-compulsive disorder (OCD) patients is associated with post-treatment OCD symptom severity. The aim of the present study was to evaluate if post-treatment symptom severity cut-offs can discriminate remitters from non-remitters in pediatric OCD patients during three years of follow-up. All participants (N = 269) from the Nordic Long-term OCD Treatment Study (Nor-dLOTS) undergoing stepped-care treatment were included. Patients were rated with the Clinical Global Impression - Severity Scale (CGI-S) one (n = 186), two (n = 167), and three years (n = 166) after first-line cognitive-behavioral therapy. Post-treatment symptom severity scores as well as percentage reductions during treatment evaluated with the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) were analyzed using receiver operating characteristics according to the CGI-S remission scores (< 2) at follow-up. Post-treatment CY-BOCS severity scores acceptably discriminated remitters from non-remitters at one-year follow-up, but poorly for the two-and three-year follow-up. Severity percentage reduction during treatment did not discriminate remis-sion status acceptably at any follow-up point. Post-treatment OCD symptom severity status seems to have little discriminative value for long-term remission status in pediatric patients. Further research is warranted to detect post-treatment factors of prognostic value.
Original language | English |
---|---|
Article number | 114906 |
Journal | Psychiatry Research |
Volume | 317 |
Number of pages | 9 |
ISSN | 0165-1781 |
DOIs | |
Publication status | Published - 2022 |
Keywords
- Stepped -care treatment
- Long-term study
- Clinical assessment
- Remission
- Children and adolescents
- Children?s Yale-brown obsessive-compulsive
- Clinical global impression scale
- COGNITIVE-BEHAVIOR THERAPY
- SIGNAL-DETECTION ANALYSIS
- DEFINING TREATMENT RESPONSE
- FOLLOW-UP
- PSYCHOMETRIC EVALUATION
- CHILDREN
- OCD
- NONRESPONDERS
- RELIABILITY
- ADOLESCENTS