Abstract
OBJECTIVE: To conduct a meta-analysis from published studies to evaluate the relationship between long working hours and the risk of cardiovascular disease (CVD).
METHODS: Among a total of 341 published studies found from publicly accessible databases, five cohort studies and six case-control studies were analyzed for the study.
RESULTS: Statistically significant heterogeneity has been observed (P = 0.037). The effect of longer working hours was significantly associated with the risk of CVD in the random-effects model of all 11 studies (odds ratio, 1.37; 95% confidence interval, 1.11 to 1.70). On the basis of meta-regression analysis, the result was not affected by the mean age, region, or the study year. The P value using Eager test was 0.701 suggesting this analysis was unlikely to have any publication bias.
CONCLUSIONS: These findings provide evidence of increased CVD with long working hours.
| Original language | English |
|---|---|
| Journal | Journal of Occupational and Environmental Medicine |
| Volume | 54 |
| Issue number | 5 |
| Pages (from-to) | 532-537 |
| Number of pages | 6 |
| ISSN | 1076-2752 |
| DOIs | |
| Publication status | Published - 2012 |
| Externally published | Yes |
Keywords
- Adult
- Aged
- Cardiovascular Diseases/epidemiology
- Confidence Intervals
- Female
- Humans
- Male
- Middle Aged
- Odds Ratio
- Time Factors
- Work Schedule Tolerance/physiology
- Young Adult