Magnesiumsulfat nedsætter risikoen for cerebral parese efter præterm fødsel

Hanne Trap Wolf; Tine Brink Henriksen; Mads Langager Larsen; Anja Pinborg; Hanne Kristine Hegaard; Jesper Sune Brok; Lene Drasbek Huusom

Magnesiumsulfat nedsætter risikoen for cerebral parese efter præterm fødsel

Translated title of the contribution: Magnesium sulphate treatment decreases the risk of cerebral palsy after preterm birth

Hanne Trap Wolf, Tine Brink Henriksen, Mads Langager Larsen, Anja Pinborg, Hanne Kristine Hegaard, Jesper Sune Brok, Lene Drasbek Huusom

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Children born preterm have an increased risk of severe morbidity, e.g. cerebral palsy (CP), compared to children born at term. CP cannot be treated, which is why a prophylactic approach is essential, as argued in this review. Six randomised controlled trials (RCTs) have provided data on MgSO4 treatment as CP neuroprotection in preterm birth, including a new RCT from Denmark. Recently, an updated meta-analysis with trial sequential analysis detected a significant neuroprotective effect of MgSO4 treatment in preterm birth. There is now sufficient evidence, that MgSO4 treatment should be used as neuroprotection in preterm birth.

Translated title of the contribution	Magnesium sulphate treatment decreases the risk of cerebral palsy after preterm birth
Original language	Danish
Article number	V06200441
Journal	Ugeskrift for Laeger
Volume	182
Issue number	47
Number of pages	8
ISSN	0041-5782
Publication status	Published - 2020

Access to Document

https://ugeskriftet.dk/files/scientific_article_files/2020-11/v06200441_web.pdf

Cite this

Magnesiumsulfat nedsætter risikoen for cerebral parese efter præterm fødsel. / Wolf, Hanne Trap; Henriksen, Tine Brink; Larsen, Mads Langager; Pinborg, Anja ; Hegaard, Hanne Kristine; Brok, Jesper Sune; Huusom, Lene Drasbek.

In: Ugeskrift for Laeger, Vol. 182, No. 47, V06200441, 2020.

Research output: Contribution to journal › Journal article › Research › peer-review

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abstract = "Children born preterm have an increased risk of severe morbidity, e.g. cerebral palsy (CP), compared to children born at term. CP cannot be treated, which is why a prophylactic approach is essential, as argued in this review. Six randomised controlled trials (RCTs) have provided data on MgSO4 treatment as CP neuroprotection in preterm birth, including a new RCT from Denmark. Recently, an updated meta-analysis with trial sequential analysis detected a significant neuroprotective effect of MgSO4 treatment in preterm birth. There is now sufficient evidence, that MgSO4 treatment should be used as neuroprotection in preterm birth.",

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AU - Wolf, Hanne Trap

AU - Henriksen, Tine Brink

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AU - Pinborg, Anja

AU - Hegaard, Hanne Kristine

AU - Brok, Jesper Sune

AU - Huusom, Lene Drasbek

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AB - Children born preterm have an increased risk of severe morbidity, e.g. cerebral palsy (CP), compared to children born at term. CP cannot be treated, which is why a prophylactic approach is essential, as argued in this review. Six randomised controlled trials (RCTs) have provided data on MgSO4 treatment as CP neuroprotection in preterm birth, including a new RCT from Denmark. Recently, an updated meta-analysis with trial sequential analysis detected a significant neuroprotective effect of MgSO4 treatment in preterm birth. There is now sufficient evidence, that MgSO4 treatment should be used as neuroprotection in preterm birth.

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