Mannan-binding lectin and mannan-binding lectin-associated serine protease 2 in acute pancreatitis

Srdan Novovic; Anders Møller Andersen; Annette Kjær Ersbøll; Lars N Jorgensen; Hans J Nielsen; Jens Christian Jensenius; Mark Berner Hansen

doi:10.1097/MPA.0b013e31821b5a72

Mannan-binding lectin and mannan-binding lectin-associated serine protease 2 in acute pancreatitis

Srdan Novovic, Anders Møller Andersen, Annette Kjær Ersbøll, Lars N Jorgensen, Hans J Nielsen, Jens Christian Jensenius, Mark Berner Hansen

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Abstract

Complement activation may play a prominent role in acute pancreatitis (AP). Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) participate in complement activation. The objective of the present study was to evaluate the role of MBL and MASP-2 as markers in AP with regard to etiology, inflammatory activity, severity, and development of multiorgan failure.

Original language	English
Journal	Pancreas
Volume	40
Issue number	7
Pages (from-to)	1097-102
Number of pages	6
ISSN	0885-3177
DOIs	https://doi.org/10.1097/MPA.0b013e31821b5a72
Publication status	Published - 2011

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10.1097/MPA.0b013e31821b5a72

Cite this

Mannan-binding lectin and mannan-binding lectin-associated serine protease 2 in acute pancreatitis. / Novovic, Srdan; Andersen, Anders Møller; Ersbøll, Annette Kjær; Jorgensen, Lars N; Nielsen, Hans J; Jensenius, Jens Christian; Hansen, Mark Berner.

In: Pancreas, Vol. 40, No. 7, 2011, p. 1097-102.

Research output: Contribution to journal › Journal article › Research › peer-review

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abstract = "Complement activation may play a prominent role in acute pancreatitis (AP). Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) participate in complement activation. The objective of the present study was to evaluate the role of MBL and MASP-2 as markers in AP with regard to etiology, inflammatory activity, severity, and development of multiorgan failure.",

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AU - Novovic, Srdan

AU - Andersen, Anders Møller

AU - Ersbøll, Annette Kjær

AU - Jorgensen, Lars N

AU - Nielsen, Hans J

AU - Jensenius, Jens Christian

AU - Hansen, Mark Berner

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AB - Complement activation may play a prominent role in acute pancreatitis (AP). Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) participate in complement activation. The objective of the present study was to evaluate the role of MBL and MASP-2 as markers in AP with regard to etiology, inflammatory activity, severity, and development of multiorgan failure.

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