Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

Michele Mariotti; Fabian Leinisch; Diana Julie Leeming; Birte Svensson; Michael J. Davies; Per Hagglund

doi:10.1021/acs.jproteome.7b00881

Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

Michele Mariotti, Fabian Leinisch, Diana Julie Leeming, Birte Svensson, Michael J. Davies, Per Hagglund

Inflammation, Metabolism and Oxidation

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

Original language	English
Journal	Journal of Proteome Research
Volume	17
Issue number	6
Pages (from-to)	2017-2027
ISSN	1535-3893
DOIs	https://doi.org/10.1021/acs.jproteome.7b00881
Publication status	Published - 2018

Keywords

mass spectrometry
LC-MS/MS
HCD
ETD
EThcD
cross-linking
photo-oxidation
peroxyl radicals
AAPH
O-18 labeling

Access to Document

10.1021/acs.jproteome.7b00881

Cite this

Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, M. J., & Hagglund, P. (2018). Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation. Journal of Proteome Research, 17(6), 2017-2027. https://doi.org/10.1021/acs.jproteome.7b00881

Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation. / Mariotti, Michele; Leinisch, Fabian; Leeming, Diana Julie; Svensson, Birte; Davies, Michael J.; Hagglund, Per.

In: Journal of Proteome Research, Vol. 17, No. 6, 2018, p. 2017-2027.

Research output: Contribution to journal › Journal article › Research › peer-review

Mariotti, M, Leinisch, F, Leeming, DJ, Svensson, B, Davies, MJ & Hagglund, P 2018, 'Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation', Journal of Proteome Research, vol. 17, no. 6, pp. 2017-2027. https://doi.org/10.1021/acs.jproteome.7b00881

Mariotti, Michele ; Leinisch, Fabian ; Leeming, Diana Julie ; Svensson, Birte ; Davies, Michael J. ; Hagglund, Per. / Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation. In: Journal of Proteome Research. 2018 ; Vol. 17, No. 6. pp. 2017-2027.

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keywords = "mass spectrometry, LC-MS/MS, HCD, ETD, EThcD, cross-linking, photo-oxidation, peroxyl radicals, AAPH, O-18 labeling",

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