Microparticle matrix encoding of beads

Morten Meldal*, Søren Flygering Christensen

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

17 Citations (Scopus)

Abstract

Reloaded matrix: Facile optical encoding of polyethylene glycol (PEC) based resins provides a direct identification of compounds in combinatorial libraries, and the structures may be correlated with bioactivity. The new technique, microparticle matrix (MPM) encoding (see picture), circumvents some problems often encountered in solid-phase combinatorial chemistry and is extremely simple to implement. (Figure Presented).

Original languageEnglish
JournalAngewandte Chemie - International Edition
Volume49
Issue number20
Pages (from-to)3473-3476
Number of pages4
ISSN1433-7851
DOIs
Publication statusPublished - 3 May 2010
Externally publishedYes

Keywords

  • Automated screening
  • Combinatorial chemistry
  • Encoding
  • Fluorescent tags
  • Peptides

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