Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes

H Reinhard; P Karl Jacobsen; Marianne Lajer; N Pedersen; N Billestrup; Thomas Mandrup-Poulsen; H-H Parving; P Rossing

doi:10.1007/s00125-010-1843-4

Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes

H Reinhard, P Karl Jacobsen, Marianne Lajer, N Pedersen, N Billestrup, Thomas Mandrup-Poulsen, H-H Parving, P Rossing

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

Abstract

Endothelial progenitor cells (EPC) augment vascular repair and neovascularisation. Patients with type 2 diabetes have reduced EPC and increased risk of cardiovascular disease (CVD), which is reduced by multifactorial intervention. Our aim, therefore, was to evaluate in type 2 diabetic patients whether the numbers of EPC derived from peripheral blood mononuclear cells is influenced by a multifactorial treatment strategy.

Original language	English
Journal	Diabetologica
Volume	53
Issue number	10
Pages (from-to)	2129-33
Number of pages	5
ISSN	1432-0428
DOIs	https://doi.org/10.1007/s00125-010-1843-4
Publication status	Published - 1 Oct 2010

Keywords

Angiotensin Receptor Antagonists
Aspirin
Cell Count
Cells, Cultured
Diabetes Mellitus, Type 2
Diet, Reducing
Endothelial Cells
Exercise Therapy
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Leukocytes, Mononuclear
Life Style
Male
Metformin
Stem Cells
Treatment Outcome

Access to Document

10.1007/s00125-010-1843-4

Cite this

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title = "Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes",

abstract = "Endothelial progenitor cells (EPC) augment vascular repair and neovascularisation. Patients with type 2 diabetes have reduced EPC and increased risk of cardiovascular disease (CVD), which is reduced by multifactorial intervention. Our aim, therefore, was to evaluate in type 2 diabetic patients whether the numbers of EPC derived from peripheral blood mononuclear cells is influenced by a multifactorial treatment strategy.",

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T1 - Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes

AU - Reinhard, H

AU - Jacobsen, P Karl

AU - Lajer, Marianne

AU - Pedersen, N

AU - Billestrup, N

AU - Mandrup-Poulsen, Thomas

AU - Parving, H-H

AU - Rossing, P

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AB - Endothelial progenitor cells (EPC) augment vascular repair and neovascularisation. Patients with type 2 diabetes have reduced EPC and increased risk of cardiovascular disease (CVD), which is reduced by multifactorial intervention. Our aim, therefore, was to evaluate in type 2 diabetic patients whether the numbers of EPC derived from peripheral blood mononuclear cells is influenced by a multifactorial treatment strategy.

KW - Angiotensin Receptor Antagonists

KW - Aspirin

KW - Cell Count

KW - Cells, Cultured

KW - Diabetes Mellitus, Type 2

KW - Diet, Reducing

KW - Endothelial Cells

KW - Exercise Therapy

KW - Female

KW - Humans

KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors

KW - Leukocytes, Mononuclear

KW - Life Style

KW - Male

KW - Metformin

KW - Stem Cells

KW - Treatment Outcome

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DO - 10.1007/s00125-010-1843-4

M3 - Journal article

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JO - Diabetologica

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