New drug-development paradigms? Opportunities and uncertainties with new government drug repurposing programmes

Johnathan Liddicoat*, Ashleigh Hamidzadeh , Kathleen Liddell, Marco Schito, David Simon, Mateo Aboy, Timo Minssen

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract


KEY MESSAGES

●Governments in the US, UK and EU have recently established seven drug-repurposing programmes that aim to overcome legal and regulatory hurdles.

●The programmes all operate in different ways, presenting a variety of opportunities for all organisations in drug development, including charities and academics.

●Perhaps more profoundly, at least three of the programmes also constitute new models of drug development, relying less on patents and private industry and more on government involvement and clinical trials run by the public sector.

●These new models could lead to relatively fast, inexpensive therapies. Yet, how effective the programmes will be and how they could be improved is uncertain, and the comparison in this paper paves the way to address these essential issues.

Original languageEnglish
JournalScience Translational Medicine
Volume16
Issue number753
ISSN1946-6234
DOIs
Publication statusPublished - 26 Jun 2024

Bibliographical note

Liddicoat J, Hamidzadeh A, Liddell K, Schito M, Simon D, Aboy M, Minssen T. New government drug repurposing programs: Opportunities and uncertainties. Sci Transl Med. 2024 Jun 26;16(753):eadl0998. doi: 10.1126/scitranslmed.adl0998. Epub 2024 Jun 26. PMID: 38924430.

Keywords

  • Faculty of Law
  • Government Programs
  • drug R&D
  • new uses
  • drug repurposing
  • Public private partnership
  • Emperical legal studies

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