New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

Anette Müllertz; Anayo Ogbonna; Shan Ren; Thomas Rades

doi:10.1111/j.2042-7158.2010.01107.x

New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

Anette Müllertz, Anayo Ogbonna, Shan Ren, Thomas Rades

Research output: Contribution to journal › Journal article › Research › peer-review

271 Citations (Scopus)

Abstract

The aim of this review is to highlight relevant considerations when implementing a rational strategy for the development of lipid and surfactant based drug delivery system and to discuss shortcomings and challenges to the current classification of these delivery systems. We also aim to offer suggestions for an improved classification system that will accommodate lipid based formulations that are not currently accommodated in the lipid formulation classification system.

Original language	English
Journal	Journal of Pharmacy and Pharmacology
Volume	62
Issue number	11
Pages (from-to)	1622-1636
Number of pages	15
ISSN	0022-3573
DOIs	https://doi.org/10.1111/j.2042-7158.2010.01107.x
Publication status	Published - 2010

Keywords

Administration, Oral
Biological Availability
Drug Delivery Systems
Emulsions
Lipids
Pharmaceutical Preparations
Solubility
Surface-Active Agents
Technology, Pharmaceutical

Access to Document

10.1111/j.2042-7158.2010.01107.x

Cite this

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abstract = "The aim of this review is to highlight relevant considerations when implementing a rational strategy for the development of lipid and surfactant based drug delivery system and to discuss shortcomings and challenges to the current classification of these delivery systems. We also aim to offer suggestions for an improved classification system that will accommodate lipid based formulations that are not currently accommodated in the lipid formulation classification system.",

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AU - Ren, Shan

AU - Rades, Thomas

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KW - Administration, Oral

KW - Biological Availability

KW - Drug Delivery Systems

KW - Emulsions

KW - Lipids

KW - Pharmaceutical Preparations

KW - Solubility

KW - Surface-Active Agents

KW - Technology, Pharmaceutical

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DO - 10.1111/j.2042-7158.2010.01107.x

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