No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects

M. A. Nauck; H. Holle; M. Kahle; A. Tytko; C. F. Deacon; J. J. Holst; J. J. Meier

doi:10.1016/j.peptides.2019.170176

No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects

M. A. Nauck, H. Holle, M. Kahle, A. Tytko, C. F. Deacon, J. J. Holst, J. J. Meier

Research output: Contribution to journal › Review › Research › peer-review

3 Citations (Scopus)

Original language	English
Article number	170176
Journal	Peptides
Volume	125
ISSN	0196-9781
DOIs	https://doi.org/10.1016/j.peptides.2019.170176
Publication status	Published - 2020

Keywords

Gastric inhibitory polypeptide
Glucose-dependent insulinotropic peptide
Tachyphylaxis
Desensitization
Insulin secretion
Hyperglycaemic clamp

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10.1016/j.peptides.2019.170176

Cite this

No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects. / Nauck, M. A.; Holle, H.; Kahle, M.; Tytko, A.; Deacon, C. F.; Holst, J. J.; Meier, J. J.

In: Peptides, Vol. 125, 170176, 2020.

Research output: Contribution to journal › Review › Research › peer-review

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title = "No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects",

keywords = "Gastric inhibitory polypeptide, Glucose-dependent insulinotropic peptide, Tachyphylaxis, Desensitization, Insulin secretion, Hyperglycaemic clamp",

author = "Nauck, {M. A.} and H. Holle and M. Kahle and A. Tytko and Deacon, {C. F.} and Holst, {J. J.} and Meier, {J. J.}",

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AU - Nauck, M. A.

AU - Holle, H.

AU - Kahle, M.

AU - Tytko, A.

AU - Deacon, C. F.

AU - Holst, J. J.

AU - Meier, J. J.

PY - 2020

Y1 - 2020

KW - Gastric inhibitory polypeptide

KW - Glucose-dependent insulinotropic peptide

KW - Tachyphylaxis

KW - Desensitization

KW - Insulin secretion

KW - Hyperglycaemic clamp

U2 - 10.1016/j.peptides.2019.170176

DO - 10.1016/j.peptides.2019.170176

M3 - Review

C2 - 31669136

VL - 125

JO - Peptides

JF - Peptides

SN - 0196-9781

M1 - 170176

ER -