Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity

Magnus S. Ågren; Thomas L. Andersen; Line Andersen; Christine Bruun Schiødt; Vikas Surve; Troels T. Andreassen; Juha  Risteli; Lennart E. Franzén; Jean-Marie Delaissé; Anne-Marie Heegaard; Lars Nannestad Jørgensen

doi:10.1007/s00384-010-1106-3

Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity

Magnus S. Ågren, Thomas L. Andersen, Line Andersen, Christine Bruun Schiødt, Vikas Surve, Troels T. Andreassen, Juha Risteli, Lennart E. Franzén, Jean-Marie Delaissé, Anne-Marie Heegaard, Lars Nannestad Jørgensen

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Abstract

Increased matrix metalloproteinase (MMP) activity has been implicated in the pathogenesis of colorectal anastomotic leakage. Tumor necrosis factor-a (TNF-a) induces MMPs and may influence anastomosis repair.

Original language	English
Journal	International Journal of Colorectal Disease
Volume	26
Issue number	3
Pages (from-to)	329-337
Number of pages	9
ISSN	0179-1958
DOIs	https://doi.org/10.1007/s00384-010-1106-3
Publication status	Published - 2011

Keywords

Former Faculty of Pharmaceutical Sciences

Access to Document

10.1007/s00384-010-1106-3

Cite this

Ågren, M. S., Andersen, T. L., Andersen, L., Schiødt, C. B., Surve, V., Andreassen, T. T., Risteli, J., Franzén, L. E., Delaissé, J-M., Heegaard, A-M., & Jørgensen, L. N. (2011). Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity. International Journal of Colorectal Disease, 26(3), 329-337. https://doi.org/10.1007/s00384-010-1106-3

Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity. / Ågren, Magnus S.; Andersen, Thomas L.; Andersen, Line; Schiødt, Christine Bruun; Surve, Vikas; Andreassen, Troels T.; Risteli, Juha ; Franzén, Lennart E.; Delaissé, Jean-Marie; Heegaard, Anne-Marie ; Jørgensen, Lars Nannestad.

In: International Journal of Colorectal Disease, Vol. 26, No. 3, 2011, p. 329-337.

Research output: Contribution to journal › Journal article › Research › peer-review

Ågren, MS, Andersen, TL, Andersen, L, Schiødt, CB, Surve, V, Andreassen, TT, Risteli, J, Franzén, LE, Delaissé, J-M, Heegaard, A-M & Jørgensen, LN 2011, 'Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity', International Journal of Colorectal Disease, vol. 26, no. 3, pp. 329-337. https://doi.org/10.1007/s00384-010-1106-3

Ågren, Magnus S. ; Andersen, Thomas L. ; Andersen, Line ; Schiødt, Christine Bruun ; Surve, Vikas ; Andreassen, Troels T. ; Risteli, Juha ; Franzén, Lennart E. ; Delaissé, Jean-Marie ; Heegaard, Anne-Marie ; Jørgensen, Lars Nannestad. / Nonselective matrix metalloproteinase but not tumor necrosis factor-a inhibition effectively preserves the early critical colon anastomotic integrity. In: International Journal of Colorectal Disease. 2011 ; Vol. 26, No. 3. pp. 329-337.

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