Occupational variation in incidence of oropharyngeal cancer in the Nordic countries

Rayan Nikkilä; Antti Mäkitie; Timo Carpén; Johnni Hansen; Sanna Heikkinen; Elsebeth Lynge; Jenny Selander; Ingrid Sivesind Mehlum; Jóhanna Eyrún Torfadottir; Tuula Salo; Eero Pukkala

doi:10.1007/s00405-023-08168-6

Occupational variation in incidence of oropharyngeal cancer in the Nordic countries

Rayan Nikkilä, Antti Mäkitie^*, Timo Carpén, Johnni Hansen, Sanna Heikkinen, Elsebeth Lynge, Jenny Selander, Ingrid Sivesind Mehlum, Jóhanna Eyrún Torfadottir, Tuula Salo, Eero Pukkala

^*Corresponding author for this work

Section of Environmental Health

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

Purpose: Evaluate the occupational variation in incidence of oropharyngeal cancer (OPC). Methods: We calculated standardized incidence ratios (SIRs) of OPC in occupational categories in the Nordic countries relative to the entire national populations. The data covered 6155 OPC cases. Results: Among men high risk of OPC was observed, among else, in waiters (SIR 6.28, 95% CI 4.68–8.26), beverage workers (SIR 3.00, 95% CI 1.72–4.88), and artistic workers (SIR 2.97, 95% CI 2.31–3.76). Among women high risk of OPC was observed in waiters (SIR 2.02, 95% CI 1.41–2.81) and packers (SIR 1.73, 95% CI 1.07–2.64). The lowest SIRs were observed in female gardeners (SIR 0.27, 95% CI 0.12–0.51) and male farmers (SIR 0.30, 95% CI 0.25–0.35). Conclusion: The 20-fold variation in incidence of OPC between occupations needs further investigation in studies with detailed information on occupational and non-occupational risk factors.

Original language	English
Journal	European Archives of Oto-Rhino-Laryngology
Volume	281
Pages (from-to)	343–350
Number of pages	8
ISSN	0937-4477
DOIs	https://doi.org/10.1007/s00405-023-08168-6
Publication status	Published - 2024

Bibliographical note

Publisher Copyright:
© 2023, The Author(s).

Keywords

Head and neck cancer
Occupational risk
OPC
Oropharyngeal cancer
Oropharynx

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10.1007/s00405-023-08168-6

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Occupational variation in incidence of oropharyngeal cancer in the Nordic countries. / Nikkilä, Rayan; Mäkitie, Antti; Carpén, Timo; Hansen, Johnni; Heikkinen, Sanna; Lynge, Elsebeth; Selander, Jenny; Mehlum, Ingrid Sivesind; Torfadottir, Jóhanna Eyrún; Salo, Tuula; Pukkala, Eero.

In: European Archives of Oto-Rhino-Laryngology, Vol. 281, 2024, p. 343–350.

Research output: Contribution to journal › Journal article › Research › peer-review

Nikkilä, Rayan ; Mäkitie, Antti ; Carpén, Timo ; Hansen, Johnni ; Heikkinen, Sanna ; Lynge, Elsebeth ; Selander, Jenny ; Mehlum, Ingrid Sivesind ; Torfadottir, Jóhanna Eyrún ; Salo, Tuula ; Pukkala, Eero. / Occupational variation in incidence of oropharyngeal cancer in the Nordic countries. In: European Archives of Oto-Rhino-Laryngology. 2024 ; Vol. 281. pp. 343–350.

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abstract = "Purpose: Evaluate the occupational variation in incidence of oropharyngeal cancer (OPC). Methods: We calculated standardized incidence ratios (SIRs) of OPC in occupational categories in the Nordic countries relative to the entire national populations. The data covered 6155 OPC cases. Results: Among men high risk of OPC was observed, among else, in waiters (SIR 6.28, 95% CI 4.68–8.26), beverage workers (SIR 3.00, 95% CI 1.72–4.88), and artistic workers (SIR 2.97, 95% CI 2.31–3.76). Among women high risk of OPC was observed in waiters (SIR 2.02, 95% CI 1.41–2.81) and packers (SIR 1.73, 95% CI 1.07–2.64). The lowest SIRs were observed in female gardeners (SIR 0.27, 95% CI 0.12–0.51) and male farmers (SIR 0.30, 95% CI 0.25–0.35). Conclusion: The 20-fold variation in incidence of OPC between occupations needs further investigation in studies with detailed information on occupational and non-occupational risk factors.",

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AU - Mäkitie, Antti

AU - Carpén, Timo

AU - Hansen, Johnni

AU - Heikkinen, Sanna

AU - Lynge, Elsebeth

AU - Selander, Jenny

AU - Mehlum, Ingrid Sivesind

AU - Torfadottir, Jóhanna Eyrún

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AU - Pukkala, Eero

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AB - Purpose: Evaluate the occupational variation in incidence of oropharyngeal cancer (OPC). Methods: We calculated standardized incidence ratios (SIRs) of OPC in occupational categories in the Nordic countries relative to the entire national populations. The data covered 6155 OPC cases. Results: Among men high risk of OPC was observed, among else, in waiters (SIR 6.28, 95% CI 4.68–8.26), beverage workers (SIR 3.00, 95% CI 1.72–4.88), and artistic workers (SIR 2.97, 95% CI 2.31–3.76). Among women high risk of OPC was observed in waiters (SIR 2.02, 95% CI 1.41–2.81) and packers (SIR 1.73, 95% CI 1.07–2.64). The lowest SIRs were observed in female gardeners (SIR 0.27, 95% CI 0.12–0.51) and male farmers (SIR 0.30, 95% CI 0.25–0.35). Conclusion: The 20-fold variation in incidence of OPC between occupations needs further investigation in studies with detailed information on occupational and non-occupational risk factors.

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