Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations

Malthe Mohl Schack; Eva Horn Moller; Anders V. Friderichsen; John F. Carpenter; Thomas Rades; Minna Groenning

doi:10.1016/j.xphs.2018.10.028

Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations

Malthe Mohl Schack, Eva Horn Moller, Anders V. Friderichsen, John F. Carpenter, Thomas Rades, Minna Groenning

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Original language	English
Journal	Journal of Pharmaceutical Sciences
Volume	108
Issue number	3
Pages (from-to)	1117-1129
ISSN	0022-3549
DOIs	https://doi.org/10.1016/j.xphs.2018.10.028
Publication status	Published - 2019

Keywords

infrared (IR) spectroscopy
microparticle(s)
protein structure(s)
insulin
biopharmaceutical characterization

Access to Document

10.1016/j.xphs.2018.10.028

Cite this

Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations. / Schack, Malthe Mohl; Moller, Eva Horn; Friderichsen, Anders V.; Carpenter, John F.; Rades, Thomas; Groenning, Minna.

In: Journal of Pharmaceutical Sciences, Vol. 108, No. 3, 2019, p. 1117-1129.

Research output: Contribution to journal › Journal article › Research › peer-review

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title = "Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations",

keywords = "infrared (IR) spectroscopy, microparticle(s), protein structure(s), insulin, biopharmaceutical characterization",

author = "Schack, {Malthe Mohl} and Moller, {Eva Horn} and Friderichsen, {Anders V.} and Carpenter, {John F.} and Thomas Rades and Minna Groenning",

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AU - Schack, Malthe Mohl

AU - Moller, Eva Horn

AU - Friderichsen, Anders V.

AU - Carpenter, John F.

AU - Rades, Thomas

AU - Groenning, Minna

PY - 2019

Y1 - 2019

KW - infrared (IR) spectroscopy

KW - microparticle(s)

KW - protein structure(s)

KW - insulin

KW - biopharmaceutical characterization

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DO - 10.1016/j.xphs.2018.10.028

M3 - Journal article

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JO - Journal of Pharmaceutical Sciences

JF - Journal of Pharmaceutical Sciences

SN - 0022-3549

IS - 3

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