Outrunning obesity with Lac-Phe?

Jens Lund; Christoffer Clemmensen; Thue W. Schwartz

doi:10.1016/j.cmet.2022.07.007

Outrunning obesity with Lac-Phe?

Jens Lund, Christoffer Clemmensen^*, Thue W. Schwartz^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate › Research › peer-review

9 Citations (Scopus)

Abstract

Lactate released from skeletal muscle during high-intensity exercise gives rise to a surge in circulating lactate-derived pseudo-dipeptide metabolites including N-lactoyl-phenylalanine (Lac-Phe). In a recent Nature paper, Li et al. use genetic and pharmacological evidence to now propose Lac-Phe to be an “exercise hormone” that suppresses appetite and obesity.

Original language	English
Journal	Cell Metabolism
Volume	34
Issue number	8
Pages (from-to)	1085-1087
Number of pages	3
ISSN	1550-4131
DOIs	https://doi.org/10.1016/j.cmet.2022.07.007
Publication status	Published - 2022

Bibliographical note

Publisher Copyright:
© 2022 Elsevier Inc.

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10.1016/j.cmet.2022.07.007

Cite this

@article{08be14c6d37f4126858bf2bcb01b551d,

title = "Outrunning obesity with Lac-Phe?",

abstract = "Lactate released from skeletal muscle during high-intensity exercise gives rise to a surge in circulating lactate-derived pseudo-dipeptide metabolites including N-lactoyl-phenylalanine (Lac-Phe). In a recent Nature paper, Li et al. use genetic and pharmacological evidence to now propose Lac-Phe to be an “exercise hormone” that suppresses appetite and obesity.",

author = "Jens Lund and Christoffer Clemmensen and Schwartz, {Thue W.}",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

doi = "10.1016/j.cmet.2022.07.007",

language = "English",

volume = "34",

pages = "1085--1087",

journal = "Cell Metabolism",

issn = "1550-4131",