Parallel artificial liquid membrane extraction: micro-scale liquid-liquid-liquid extraction in the 96-well format

Astrid Gjelstad; Knut Einar Rasmussen; Marthe Petrine Parmer; Stig Pedersen-Bjergaard

doi:10.4155/bio.13.59

Parallel artificial liquid membrane extraction: micro-scale liquid-liquid-liquid extraction in the 96-well format

Astrid Gjelstad, Knut Einar Rasmussen, Marthe Petrine Parmer, Stig Pedersen-Bjergaard

Analytical Biosciences

Research output: Contribution to journal › Journal article › Research › peer-review

64 Citations (Scopus)

Abstract

This paper reports development of a new approach towards analytical liquid-liquid-liquid membrane extraction termed parallel artificial liquid membrane extraction. A donor plate and acceptor plate create a sandwich, in which each sample (human plasma) and acceptor solution is separated by an artificial liquid membrane. Parallel artificial liquid membrane extraction is a modification of hollow-fiber liquid-phase microextraction, where the hollow fibers are replaced by flat membranes in a 96-well plate format.

Original language	English
Journal	Bioanalysis
Volume	5
Issue number	11
Pages (from-to)	1377-85
Number of pages	9
ISSN	1757-6180
DOIs	https://doi.org/10.4155/bio.13.59
Publication status	Published - Jun 2013

Keywords

Chromatography, Liquid
Equipment Design
Humans
Limit of Detection
Liquid Phase Microextraction
Membranes, Artificial
Pharmaceutical Preparations
Tandem Mass Spectrometry

Access to Document

10.4155/bio.13.59

Cite this

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title = "Parallel artificial liquid membrane extraction: micro-scale liquid-liquid-liquid extraction in the 96-well format",

abstract = "This paper reports development of a new approach towards analytical liquid-liquid-liquid membrane extraction termed parallel artificial liquid membrane extraction. A donor plate and acceptor plate create a sandwich, in which each sample (human plasma) and acceptor solution is separated by an artificial liquid membrane. Parallel artificial liquid membrane extraction is a modification of hollow-fiber liquid-phase microextraction, where the hollow fibers are replaced by flat membranes in a 96-well plate format.",

keywords = "Chromatography, Liquid, Equipment Design, Humans, Limit of Detection, Liquid Phase Microextraction, Membranes, Artificial, Pharmaceutical Preparations, Tandem Mass Spectrometry",

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AU - Pedersen-Bjergaard, Stig

PY - 2013/6

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AB - This paper reports development of a new approach towards analytical liquid-liquid-liquid membrane extraction termed parallel artificial liquid membrane extraction. A donor plate and acceptor plate create a sandwich, in which each sample (human plasma) and acceptor solution is separated by an artificial liquid membrane. Parallel artificial liquid membrane extraction is a modification of hollow-fiber liquid-phase microextraction, where the hollow fibers are replaced by flat membranes in a 96-well plate format.

KW - Chromatography, Liquid

KW - Equipment Design

KW - Humans

KW - Limit of Detection

KW - Liquid Phase Microextraction

KW - Membranes, Artificial

KW - Pharmaceutical Preparations

KW - Tandem Mass Spectrometry

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