Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

Helle Hald; Peter Naur; Darryl Scott Pickering; Desiree Sprogøe; Ulf Madsen; Daniel B. Timmermann; Philip K. Ahring; Tommy Liljefors; Arne Schousboe; Jan Egebjerg; Michael Gajhede; Jette Sandholm Jensen Kastrup

doi:10.1074/jbc.M700137200

Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

Helle Hald, Peter Naur, Darryl Scott Pickering, Desiree Sprogøe, Ulf Madsen, Daniel B. Timmermann, Philip K. Ahring, Tommy Liljefors, Arne Schousboe, Jan Egebjerg, Michael Gajhede, Jette Sandholm Jensen Kastrup

Research output: Contribution to journal › Journal article › Research › peer-review

49 Citations (Scopus)

Original language	English
Journal	Journal of Biological Chemistry
Volume	282
Issue number	35
Pages (from-to)	25726-25736
ISSN	0021-9258
DOIs	https://doi.org/10.1074/jbc.M700137200
Publication status	Published - 2007

Keywords

Former Faculty of Pharmaceutical Sciences

Access to Document

10.1074/jbc.M700137200

Cite this

Hald, H., Naur, P., Pickering, D. S., Sprogøe, D., Madsen, U., Timmermann, D. B., Ahring, P. K., Liljefors, T., Schousboe, A., Egebjerg, J., Gajhede, M., & Kastrup, J. S. J. (2007). Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. Journal of Biological Chemistry, 282(35), 25726-25736. https://doi.org/10.1074/jbc.M700137200

Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. / Hald, Helle; Naur, Peter; Pickering, Darryl Scott et al.
In: Journal of Biological Chemistry, Vol. 282, No. 35, 2007, p. 25726-25736.

Research output: Contribution to journal › Journal article › Research › peer-review

Hald, H, Naur, P, Pickering, DS, Sprogøe, D, Madsen, U, Timmermann, DB, Ahring, PK, Liljefors, T, Schousboe, A, Egebjerg, J, Gajhede, M & Kastrup, JSJ 2007, 'Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid', Journal of Biological Chemistry, vol. 282, no. 35, pp. 25726-25736. https://doi.org/10.1074/jbc.M700137200

Hald H, Naur P, Pickering DS, Sprogøe D, Madsen U, Timmermann DB et al. Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. Journal of Biological Chemistry. 2007;282(35):25726-25736. doi: 10.1074/jbc.M700137200

@article{88dc59b0d0e611dcbee902004c4f4f50,

title = "Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid",

keywords = "Former Faculty of Pharmaceutical Sciences",

author = "Helle Hald and Peter Naur and Pickering, {Darryl Scott} and Desiree Sprog{\o}e and Ulf Madsen and Timmermann, {Daniel B.} and Ahring, {Philip K.} and Tommy Liljefors and Arne Schousboe and Jan Egebjerg and Michael Gajhede and Kastrup, {Jette Sandholm Jensen}",

year = "2007",

doi = "10.1074/jbc.M700137200",

language = "English",

volume = "282",

pages = "25726--25736",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology, Inc.",

number = "35",

}

TY - JOUR

T1 - Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5

T2 - Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

AU - Hald, Helle

AU - Naur, Peter

AU - Pickering, Darryl Scott

AU - Sprogøe, Desiree

AU - Madsen, Ulf

AU - Timmermann, Daniel B.

AU - Ahring, Philip K.

AU - Liljefors, Tommy

AU - Schousboe, Arne

AU - Egebjerg, Jan

AU - Gajhede, Michael

AU - Kastrup, Jette Sandholm Jensen

PY - 2007

Y1 - 2007

KW - Former Faculty of Pharmaceutical Sciences

U2 - 10.1074/jbc.M700137200

DO - 10.1074/jbc.M700137200

M3 - Journal article

C2 - 17581823

SN - 0021-9258

VL - 282

SP - 25726

EP - 25736

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 35

ER -