Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues

Esben M. Bech; Manuel C. Martos-Maldonado; Pernille Wismann; Kasper K. Sorensen; Soren Blok van Witteloostuijn; Mikkel B. Thygesen; Niels Vrang; Jacob Jelsing; Soren L. Pedersen; Knud J. Jensen

doi:10.1021/acs.jmedchem.7b00787

Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues

Esben M. Bech, Manuel C. Martos-Maldonado, Pernille Wismann, Kasper K. Sorensen, Soren Blok van Witteloostuijn, Mikkel B. Thygesen, Niels Vrang, Jacob Jelsing, Soren L. Pedersen, Knud J. Jensen

Department of Chemistry

Research output: Contribution to journal › Journal article › Research › peer-review

34 Citations (Scopus)

Original language	English
Journal	Journal of Medicinal Chemistry
Volume	60
Issue number	17
Pages (from-to)	7434-7446
Number of pages	13
ISSN	0022-2623
DOIs	https://doi.org/10.1021/acs.jmedchem.7b00787
Publication status	Published - 2017

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10.1021/acs.jmedchem.7b00787

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Bech, E. M., Martos-Maldonado, M. C., Wismann, P., Sorensen, K. K., van Witteloostuijn, S. B., Thygesen, M. B., Vrang, N., Jelsing, J., Pedersen, S. L., & Jensen, K. J. (2017). Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues. Journal of Medicinal Chemistry, 60(17), 7434-7446. https://doi.org/10.1021/acs.jmedchem.7b00787

Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues. / Bech, Esben M.; Martos-Maldonado, Manuel C.; Wismann, Pernille et al.
In: Journal of Medicinal Chemistry, Vol. 60, No. 17, 2017, p. 7434-7446.

Research output: Contribution to journal › Journal article › Research › peer-review

Bech, EM, Martos-Maldonado, MC, Wismann, P, Sorensen, KK, van Witteloostuijn, SB, Thygesen, MB, Vrang, N, Jelsing, J, Pedersen, SL & Jensen, KJ 2017, 'Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues', Journal of Medicinal Chemistry, vol. 60, no. 17, pp. 7434-7446. https://doi.org/10.1021/acs.jmedchem.7b00787

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author = "Bech, {Esben M.} and Martos-Maldonado, {Manuel C.} and Pernille Wismann and Sorensen, {Kasper K.} and {van Witteloostuijn}, {Soren Blok} and Thygesen, {Mikkel B.} and Niels Vrang and Jacob Jelsing and Pedersen, {Soren L.} and Jensen, {Knud J.}",

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AU - Martos-Maldonado, Manuel C.

AU - Wismann, Pernille

AU - Sorensen, Kasper K.

AU - van Witteloostuijn, Soren Blok

AU - Thygesen, Mikkel B.

AU - Vrang, Niels

AU - Jelsing, Jacob

AU - Pedersen, Soren L.

AU - Jensen, Knud J.

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