Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries

Preet S Chadha; Friederike Zunke; Alison J Davis; Thomas Andrew Jepps; Joannes T M Linders; Michael Schwake; Rob Towart; Iain A Greenwood

doi:10.1111/j.1476-5381.2012.01863.x

Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries

Preet S Chadha, Friederike Zunke, Alison J Davis, Thomas Andrew Jepps, Joannes T M Linders, Michael Schwake, Rob Towart, Iain A Greenwood

Physiology of circulation, kidney and lung

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

Abstract

The aim of this study was to characterize the functional impact of KCNQ1-encoded voltage-dependent potassium channels (K(v)7.1) in the vasculature.

Original language	English
Journal	British Journal of Pharmacology
Volume	166
Issue number	4
Pages (from-to)	1377-87
Number of pages	11
ISSN	0007-1188
DOIs	https://doi.org/10.1111/j.1476-5381.2012.01863.x
Publication status	Published - Jun 2012

Keywords

Animals
Aorta, Thoracic
Female
Humans
KCNQ Potassium Channels
KCNQ1 Potassium Channel
Male
Membrane Potentials
Mesenteric Arteries
Oocytes
Potassium Channel Blockers
Pulmonary Artery
Rats
Rats, Wistar
Recombinant Proteins
Vasoconstrictor Agents
Vasodilator Agents
Xenopus laevis

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10.1111/j.1476-5381.2012.01863.x

Cite this

Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries. / Chadha, Preet S; Zunke, Friederike; Davis, Alison J; Jepps, Thomas Andrew; Linders, Joannes T M; Schwake, Michael; Towart, Rob; Greenwood, Iain A.

In: British Journal of Pharmacology, Vol. 166, No. 4, 06.2012, p. 1377-87.

Research output: Contribution to journal › Journal article › Research › peer-review

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abstract = "The aim of this study was to characterize the functional impact of KCNQ1-encoded voltage-dependent potassium channels (K(v)7.1) in the vasculature.",

keywords = "Animals, Aorta, Thoracic, Female, Humans, KCNQ Potassium Channels, KCNQ1 Potassium Channel, Male, Membrane Potentials, Mesenteric Arteries, Oocytes, Potassium Channel Blockers, Pulmonary Artery, Rats, Rats, Wistar, Recombinant Proteins, Vasoconstrictor Agents, Vasodilator Agents, Xenopus laevis",

author = "Chadha, {Preet S} and Friederike Zunke and Davis, {Alison J} and Jepps, {Thomas Andrew} and Linders, {Joannes T M} and Michael Schwake and Rob Towart and Greenwood, {Iain A}",

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AU - Linders, Joannes T M

AU - Schwake, Michael

AU - Towart, Rob

AU - Greenwood, Iain A

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KW - Membrane Potentials

KW - Mesenteric Arteries

KW - Oocytes

KW - Potassium Channel Blockers

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KW - Vasodilator Agents

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