Abstract
Aim: To compare the measurement of proANP and proBNP in plasma for the diagnosis of heart failure. Methods: In the PubMed search, a process of combining subject headings and terms regarding comparison of natriuretic peptides (proANP and proBNP) was performed. Results: 21 abstracts from research articles were screened with 14 articles assessed for eligibility. 11 papers were included for final analysis. We report comparable diagnostic accuracies of N-Terminal proBNP and mid-regional proANP. Older methods for proANP measurement seem obsolete. Conclusion: Similar diagnostic performance of proANP and proBNP measurement for the diagnosis of heart failure was identified. Consequently, mid-regional proANP can be used when considering a diagnosis of heart failure.
| Original language | English |
|---|---|
| Journal | Biomarkers in Medicine |
| Volume | 13 |
| Issue number | 13 |
| Pages (from-to) | 1129-1135 |
| Number of pages | 7 |
| ISSN | 1752-0363 |
| DOIs | |
| Publication status | Published - 2019 |
Keywords
- ANP
- biomarkers
- BNP
- heart failure
- MR-proANP
- natriuretic peptide
- NT-proBNP