Protein materials as sustainable non- and minimally invasive strategies for biomedical applications

Mai Bay Stie; Kleopatra Kalouta; Valeria Vetri; Vito Foderà

doi:10.1016/j.jconrel.2022.02.016

Protein materials as sustainable non- and minimally invasive strategies for biomedical applications

Mai Bay Stie^*, Kleopatra Kalouta, Valeria Vetri, Vito Foderà^*

^*Corresponding author for this work

Drug Delivery and Biophysics of Biopharmaceuticals

Research output: Contribution to journal › Review › Research › peer-review

25 Citations (Scopus)

28 Downloads (Pure)

Abstract

Protein-based materials have found applications in a wide range of biomedical fields because of their biocompatibility, biodegradability and great versatility. Materials of different physical forms including particles, hydrogels, films, fibers and microneedles have been fabricated e.g. as carriers for drug delivery, factors to promote wound healing and as structural support for the generation of new tissue. This review aims at providing an overview of the current scientific knowledge on protein-based materials, and selected preclinical and clinical studies will be reviewed in depth as examples of the latest progress within the field of protein-based materials, specifically focusing on non- and minimally invasive strategies mainly for topical application.

Original language	English
Journal	Journal of Controlled Release
Volume	344
Pages (from-to)	12-25
ISSN	0168-3659
DOIs	https://doi.org/10.1016/j.jconrel.2022.02.016
Publication status	Published - 2022

Bibliographical note

Funding Information:
MBS, KK and VF acknowledge VILLUM FONDEN for the Villum Young Investigator Grant “Protein superstructure as Smart Biomaterials (ProSmart)” 2018-2023 (project number: 19175 ). KK and VV acknowledge University of Palermo (FFR – PROMETA) for financial support.

Publisher Copyright:
© 2022 The Authors

Keywords

Biomaterial
Drug delivery
Non-invasive
Protein-based
Topical

Access to Document

10.1016/j.jconrel.2022.02.016

FulltextFinal published version, 3.11 MBLicence: CC BY

Cite this

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title = "Protein materials as sustainable non- and minimally invasive strategies for biomedical applications",

abstract = "Protein-based materials have found applications in a wide range of biomedical fields because of their biocompatibility, biodegradability and great versatility. Materials of different physical forms including particles, hydrogels, films, fibers and microneedles have been fabricated e.g. as carriers for drug delivery, factors to promote wound healing and as structural support for the generation of new tissue. This review aims at providing an overview of the current scientific knowledge on protein-based materials, and selected preclinical and clinical studies will be reviewed in depth as examples of the latest progress within the field of protein-based materials, specifically focusing on non- and minimally invasive strategies mainly for topical application.",

keywords = "Biomaterial, Drug delivery, Non-invasive, Protein-based, Topical",

author = "Stie, {Mai Bay} and Kleopatra Kalouta and Valeria Vetri and Vito Foder{\`a}",

note = "Funding Information: MBS, KK and VF acknowledge VILLUM FONDEN for the Villum Young Investigator Grant “Protein superstructure as Smart Biomaterials (ProSmart)” 2018-2023 (project number: 19175 ). KK and VV acknowledge University of Palermo (FFR – PROMETA) for financial support. Publisher Copyright: {\textcopyright} 2022 The Authors",

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AU - Kalouta, Kleopatra

AU - Vetri, Valeria

AU - Foderà, Vito

N1 - Funding Information: MBS, KK and VF acknowledge VILLUM FONDEN for the Villum Young Investigator Grant “Protein superstructure as Smart Biomaterials (ProSmart)” 2018-2023 (project number: 19175 ). KK and VV acknowledge University of Palermo (FFR – PROMETA) for financial support. Publisher Copyright: © 2022 The Authors

PY - 2022

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N2 - Protein-based materials have found applications in a wide range of biomedical fields because of their biocompatibility, biodegradability and great versatility. Materials of different physical forms including particles, hydrogels, films, fibers and microneedles have been fabricated e.g. as carriers for drug delivery, factors to promote wound healing and as structural support for the generation of new tissue. This review aims at providing an overview of the current scientific knowledge on protein-based materials, and selected preclinical and clinical studies will be reviewed in depth as examples of the latest progress within the field of protein-based materials, specifically focusing on non- and minimally invasive strategies mainly for topical application.

AB - Protein-based materials have found applications in a wide range of biomedical fields because of their biocompatibility, biodegradability and great versatility. Materials of different physical forms including particles, hydrogels, films, fibers and microneedles have been fabricated e.g. as carriers for drug delivery, factors to promote wound healing and as structural support for the generation of new tissue. This review aims at providing an overview of the current scientific knowledge on protein-based materials, and selected preclinical and clinical studies will be reviewed in depth as examples of the latest progress within the field of protein-based materials, specifically focusing on non- and minimally invasive strategies mainly for topical application.

KW - Biomaterial

KW - Drug delivery

KW - Non-invasive

KW - Protein-based

KW - Topical

U2 - 10.1016/j.jconrel.2022.02.016

DO - 10.1016/j.jconrel.2022.02.016

M3 - Review

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AN - SCOPUS:85125006562

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