Pulmonary intravascular macrophages in the pathogenesis of bovine pulmonary lesions caused by Actinomyces pyogenes

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    Abstract

    Rabbit antisera raised against somatic antigens from two strains of Actinomyces pyogenes reacted specifically in a peroxidase anti-peroxidase technique which was developed for the location of the bacteria in formalin-fixed tissues. The technique was applied on experimental murine and spontaneous bovine lesions caused by A. pyogenes. By electron microscopy and immunohistochemistry it was demonstrated that pulmonary intravascular macrophages play a role in the uptake of A. pyogenes from the blood, and in the production of pyaemic pulmonary lesions
    Original languageEnglish
    JournalJournal of Comparative Pathology
    Volume112
    Issue number2
    Pages (from-to)197-206
    Number of pages10
    ISSN0021-9975
    Publication statusPublished - 1995

    Keywords

    • Former LIFE faculty
    • pulmonary intravascular macrophages
    • Arcanobacterium pyogenes
    • pyaemia

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