QuantiFERON®-TB gold in-tube performance for diagnosing active tuberculosis in children and adults in a high burden setting

Michala Vaaben Rose, Godfather Kimaro, Thomas N Nissen, Inge Kroidl, Michael Hoelscher, Ib C Bygbjerg, Sayoki G Mfinanga, Pernille Ravn

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    Abstract

    To determine whether QuantiFERON®-TB Gold In-Tube (QFT) can contribute to the diagnosis of active tuberculosis (TB) in children in a high-burden setting and to assess the performance of QFT and tuberculin skin test (TST) in a prospective cohort of TB suspect children compared to adults with confirmed TB in Tanzania.
    Original languageEnglish
    Article numbere37851
    JournalPLOS ONE
    Volume7
    Issue number7
    Number of pages1
    ISSN1932-6203
    DOIs
    Publication statusPublished - Jul 2012

    Keywords

    • Acute Disease
    • Adolescent
    • Adult
    • Age Factors
    • Child
    • Child, Preschool
    • Coinfection
    • Female
    • HIV
    • HIV Infections
    • Humans
    • Immunocompromised Host
    • Infant
    • Interferon-gamma
    • Male
    • Mycobacterium tuberculosis
    • Reagent Kits, Diagnostic
    • Sensitivity and Specificity
    • Survival Rate
    • Tanzania
    • Tuberculin Test
    • Tuberculosis, Pulmonary

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