Reduced cannabinoid receptor 1 protein in subcutaneous adipose tissue of obese

Marianne Faurholt Bennetzen, Thomas Svava Nielsen, S K Paulsen, J Bendix, S Fisker, N Jessen, S Lund, Bjørn Richelsen, S B Pedersen

Research output: Contribution to journalJournal articleResearchpeer-review

17 Citations (Scopus)

Abstract

Cannabinoid 1 receptors are identified in various tissues involved in the internal metabolism including adipose tissue and the endocannabinoid system is claimed to be overactive in the obese state. To study the potential involvement of cannabinoid receptor 1 in the endocannabinoid system over-activity in adipose tissue in the obese state, we investigated the cannabinoid receptor 1 levels in adipose tissue from different fat depots in lean and obese humans.
Original languageEnglish
JournalEuropean Journal of Clinical Investigation
Volume40
Issue number2
Pages (from-to)121-6
Number of pages6
ISSN0014-2972
DOIs
Publication statusPublished - Feb 2010
Externally publishedYes

Keywords

  • Adipocytes
  • Adult
  • Blotting, Western
  • Female
  • Humans
  • Intra-Abdominal Fat
  • Male
  • Middle Aged
  • Obesity
  • RNA, Messenger
  • Receptors, Cannabinoid
  • Reverse Transcriptase Polymerase Chain Reaction
  • Subcutaneous Fat

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