Abstract
Severe hypoglycemia after Roux-en-Y gastric bypass surgery (RYGB) is an increasingly recognized condition, characterized by neuroglycopenia and inappropriately elevated insulin concentrations that occur primarily in the postprandial state. Both pathophysiology and treatment of this disorder remain elusive, but it has been postulated that hyperplasia and/or hypertrophy of beta-cells due to morbid obesity and/or postsurgical nesidioblastosis may contribute.
Original language | English |
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Journal | Journal of Clinical Endocrinology and Metabolism |
Volume | 95 |
Issue number | 4 |
Pages (from-to) | 1851-5 |
Number of pages | 5 |
ISSN | 0021-972X |
DOIs | |
Publication status | Published - Apr 2010 |
Keywords
- Adult
- Blood Glucose
- Body Mass Index
- Female
- Gastric Bypass
- Gastric Inhibitory Polypeptide
- Glucagon
- Glucagon-Like Peptide 1
- Humans
- Hyperinsulinism
- Hypoglycemia
- Insulin
- Nutritional Status
- Obesity, Morbid
- Postoperative Complications