Samspillet mellem mikrobiota og immunsystemet ved kolorektal cancer

Translated title of the contribution: Interaction between microbiota and immune system in colorectal cancer

Hans Raskov, Thomas Bjarnsholt, Mahdi Alamili, Kasper Nørskov Kragh, Ismail Gögenur*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

3 Citations (Scopus)

Abstract

In vivo- and in vitro research accumulate mounting evidence, that the interaction between the colorectal microbiota and the immune system plays an important role in the development and progression of colorectal cancer and for the treatment outcomes. In future, modulation of the microbiota and immune system will, by all accounts, become important targets for prevention and treatment of colorectal cancer. In this review, we summarise current knowledge on bacterial drivers, biofilm formation, colon cancer sidedness and oncological treatment of colorectal cancer including the use of checkpoint inhibitors.

Translated title of the contributionInteraction between microbiota and immune system in colorectal cancer
Original languageDanish
Article numberV04180253
JournalUgeskrift for Laeger
Volume180
Issue number45
ISSN0041-5782
Publication statusPublished - 5 Nov 2018

Cite this