SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

Jingying Liu; Ulrich Werner; Mario Funke; Melissa Besenius; Lasse Saaby; Mathias Fano; Huiling Mu; Anette Mullertz

doi:10.1016/j.ijpharm.2019.02.014

SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

Jingying Liu, Ulrich Werner, Mario Funke, Melissa Besenius, Lasse Saaby, Mathias Fano, Huiling Mu, Anette Mullertz

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

Original language	English
Journal	International Journal of Pharmaceutics
Volume	560
Pages (from-to)	377-384
ISSN	0378-5173
DOIs	https://doi.org/10.1016/j.ijpharm.2019.02.014
Publication status	Published - 5 Apr 2019

Keywords

Insulin
Intestinal barrier
Self-emulsifying drug delivery systems
Caco-2 monolayers
Caco-2/HT29-MTX co-culture monolayers
Intra-jejunal administration
Monoacyl phosphatidylcholine

Access to Document

10.1016/j.ijpharm.2019.02.014

Cite this

SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats. / Liu, Jingying; Werner, Ulrich; Funke, Mario; Besenius, Melissa; Saaby, Lasse; Fano, Mathias; Mu, Huiling ; Mullertz, Anette.

In: International Journal of Pharmaceutics, Vol. 560, 05.04.2019, p. 377-384.

Research output: Contribution to journal › Journal article › Research › peer-review

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title = "SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats",

keywords = "Insulin, Intestinal barrier, Self-emulsifying drug delivery systems, Caco-2 monolayers, Caco-2/HT29-MTX co-culture monolayers, Intra-jejunal administration, Monoacyl phosphatidylcholine",

author = "Jingying Liu and Ulrich Werner and Mario Funke and Melissa Besenius and Lasse Saaby and Mathias Fano and Huiling Mu and Anette Mullertz",

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AU - Werner, Ulrich

AU - Funke, Mario

AU - Besenius, Melissa

AU - Saaby, Lasse

AU - Fano, Mathias

AU - Mu, Huiling

AU - Mullertz, Anette

PY - 2019/4/5

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KW - Insulin

KW - Intestinal barrier

KW - Self-emulsifying drug delivery systems

KW - Caco-2 monolayers

KW - Caco-2/HT29-MTX co-culture monolayers

KW - Intra-jejunal administration

KW - Monoacyl phosphatidylcholine

U2 - 10.1016/j.ijpharm.2019.02.014

DO - 10.1016/j.ijpharm.2019.02.014

M3 - Journal article

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VL - 560

SP - 377

EP - 384

JO - International Journal of Pharmaceutics

JF - International Journal of Pharmaceutics

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