Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro

Carsten Uhd Nielsen, Sidsel Balsgaard Frølund, S Abdulhadi, H Sari, L Langthaler, Mark Klitgaard Nøhr, M A Kall, B Brodin, R Holm

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8 Citations (Scopus)

Abstract

Intestinal nutrient transporters may mediate the uptake of drugs. The aim of this study was to investigate whether sertraline interacts with the intestinal proton-coupled amino acid transporter 1 PAT1 (SLC36A1).
Original languageEnglish
JournalBritish Journal of Pharmacology
Volume170
Issue number5
Pages (from-to)1041-52
Number of pages12
ISSN0007-1188
DOIs
Publication statusPublished - Nov 2013

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