Signaling pathways regulating murine pancreatic development

Palle Serup

doi:10.1016/j.semcdb.2012.06.004

Signaling pathways regulating murine pancreatic development

Palle Serup

Research output: Contribution to journal › Review › peer-review

27 Citations (Scopus)

Abstract

The recent decades have seen a huge expansion in our knowledge about pancreatic development. Numerous lineage-restricted transcription factor genes have been identified and much has been learned about their function. Similarly, numerous signaling pathways important for pancreas development have been identified and the specific roles have been investigated by genetic and cell biological methods. The present review presents an overview of the principal signaling pathways involved in regulating murine pancreatic growth, morphogenesis, and cell differentiation.

Original language	English
Journal	Seminars in Cell and Developmental Biology
Volume	23
Issue number	6
Pages (from-to)	663-72
Number of pages	10
ISSN	1084-9521
DOIs	https://doi.org/10.1016/j.semcdb.2012.06.004
Publication status	Published - 1 Aug 2012

Keywords

Animals
Epithelium
Mesoderm
Mice
Organogenesis
Pancreas
Receptor Protein-Tyrosine Kinases
Signal Transduction

Access to Document

10.1016/j.semcdb.2012.06.004

http://www.sciencedirect.com.ep.fjernadgang.kb.dk/science/article/pii/S1084952112001140

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Check availability at the Royal Danish Library

Cite this

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title = "Signaling pathways regulating murine pancreatic development",

abstract = "The recent decades have seen a huge expansion in our knowledge about pancreatic development. Numerous lineage-restricted transcription factor genes have been identified and much has been learned about their function. Similarly, numerous signaling pathways important for pancreas development have been identified and the specific roles have been investigated by genetic and cell biological methods. The present review presents an overview of the principal signaling pathways involved in regulating murine pancreatic growth, morphogenesis, and cell differentiation.",

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AB - The recent decades have seen a huge expansion in our knowledge about pancreatic development. Numerous lineage-restricted transcription factor genes have been identified and much has been learned about their function. Similarly, numerous signaling pathways important for pancreas development have been identified and the specific roles have been investigated by genetic and cell biological methods. The present review presents an overview of the principal signaling pathways involved in regulating murine pancreatic growth, morphogenesis, and cell differentiation.

KW - Animals

KW - Epithelium

KW - Mesoderm

KW - Mice

KW - Organogenesis

KW - Pancreas

KW - Receptor Protein-Tyrosine Kinases

KW - Signal Transduction

U2 - 10.1016/j.semcdb.2012.06.004

DO - 10.1016/j.semcdb.2012.06.004

M3 - Review

C2 - 22728666

SN - 1084-9521

VL - 23

SP - 663

EP - 672

JO - Seminars in Cell and Developmental Biology

JF - Seminars in Cell and Developmental Biology

IS - 6

ER -