Solid-phase synthesis of 3-amino-2-pyrazolines

Lars O. Lyngsø; John Nielsen

doi:10.1016/S0040-4039(98)01158-7

Solid-phase synthesis of 3-amino-2-pyrazolines

Lars O. Lyngsø, John Nielsen^*

^*Corresponding author for this work

Natural Products and Peptides

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)

Abstract

The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.

Original language	English
Journal	Tetrahedron Letters
Volume	39
Issue number	32
Pages (from-to)	5845-5848
Number of pages	4
ISSN	0040-4039
DOIs	https://doi.org/10.1016/S0040-4039(98)01158-7
Publication status	Published - 6 Aug 1998

Access to Document

10.1016/S0040-4039(98)01158-7

http://www.scopus.com/inward/record.url?scp=0032490961&partnerID=8YFLogxK

Library access?

Check availability at the Royal Danish Library

Cite this

@article{16f344785673472fa2f936aff4e52f97,

title = "Solid-phase synthesis of 3-amino-2-pyrazolines",

abstract = "The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.",

author = "Lyngs{\o}, {Lars O.} and John Nielsen",

year = "1998",

month = aug,

day = "6",

doi = "10.1016/S0040-4039(98)01158-7",

language = "English",

volume = "39",

pages = "5845--5848",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Pergamon Press",

number = "32",

}

TY - JOUR

T1 - Solid-phase synthesis of 3-amino-2-pyrazolines

AU - Lyngsø, Lars O.

AU - Nielsen, John

PY - 1998/8/6

Y1 - 1998/8/6

N2 - The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.

AB - The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.

U2 - 10.1016/S0040-4039(98)01158-7

DO - 10.1016/S0040-4039(98)01158-7

M3 - Journal article

AN - SCOPUS:0032490961

SN - 0040-4039

VL - 39

SP - 5845

EP - 5848

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 32

ER -