Solid-state analysis for pharmaceuticals: Pathways to feasible and meaningful analysis

Jukka Rantanen*, Thomas Rades, Clare Strachan

*Corresponding author for this work

Research output: Contribution to journalReviewResearchpeer-review

1 Citation (Scopus)
23 Downloads (Pure)

Abstract

The solid state of matter is the preferred starting point for designing a pharmaceutical product. This is driven by both patient preferences and the relative ease of supplying a solid pharmaceutical product with desired quality and performance. Solid form diversity is increasingly prevalent as a crucial element in designing these products, which underpins the importance of solid-state analytical methods. This paper provides a critical analysis of challenges related to solid-state analytics, as well as considerations and suggestions for feasible and meaningful pharmaceutical analysis.

Original languageEnglish
Article number115649
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume236
Number of pages7
ISSN0731-7085
DOIs
Publication statusPublished - 2023

Keywords

  • Analytical techniques
  • Dosage form
  • Process analytics
  • Product performance
  • Sample preparation
  • Solid-state properties

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