Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus

Toke Bek; Peter Friis Jeppesen; Jørgen K. Kanters

doi:10.1167/iovs.12-11182

Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus

Toke Bek, Peter Friis Jeppesen, Jørgen K. Kanters

Physiology of circulation, kidney and lung

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

Abstract

Diabetic retinopathy is characterized by morphological changes in the retina secondary to disturbances in retinal blood flow. Vasomotion is a mechanism for regulating blood flow by spontaneous oscillations in the diameter of retinal resistance arterioles, and has been shown to be disturbed outside the eye in diabetic patients. Therefore, the purpose of the present study was to characterize spontaneous oscillations in the diameter of retinal arterioles in normal persons and in persons with different severity of diabetic retinopathy.

Original language	English
Journal	Investigative Ophthalmology & Visual Science
Volume	54
Issue number	1
Pages (from-to)	636-40
Number of pages	5
ISSN	0146-0404
DOIs	https://doi.org/10.1167/iovs.12-11182
Publication status	Published - 21 Jan 2013

Keywords

Arterioles
Blood Flow Velocity
Blood Pressure
Diabetes Mellitus, Type 2
Diabetic Retinopathy
Exercise
Female
Heart Rate
Homeostasis
Humans
Male
Middle Aged
Regional Blood Flow
Retinal Artery
Vasodilation
Video Recording

Access to Document

10.1167/iovs.12-11182

Cite this

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title = "Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus",

abstract = "Diabetic retinopathy is characterized by morphological changes in the retina secondary to disturbances in retinal blood flow. Vasomotion is a mechanism for regulating blood flow by spontaneous oscillations in the diameter of retinal resistance arterioles, and has been shown to be disturbed outside the eye in diabetic patients. Therefore, the purpose of the present study was to characterize spontaneous oscillations in the diameter of retinal arterioles in normal persons and in persons with different severity of diabetic retinopathy.",

keywords = "Arterioles, Blood Flow Velocity, Blood Pressure, Diabetes Mellitus, Type 2, Diabetic Retinopathy, Exercise, Female, Heart Rate, Homeostasis, Humans, Male, Middle Aged, Regional Blood Flow, Retinal Artery, Vasodilation, Video Recording",

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T1 - Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus

AU - Bek, Toke

AU - Jeppesen, Peter Friis

AU - Kanters, Jørgen K.

PY - 2013/1/21

Y1 - 2013/1/21

N2 - Diabetic retinopathy is characterized by morphological changes in the retina secondary to disturbances in retinal blood flow. Vasomotion is a mechanism for regulating blood flow by spontaneous oscillations in the diameter of retinal resistance arterioles, and has been shown to be disturbed outside the eye in diabetic patients. Therefore, the purpose of the present study was to characterize spontaneous oscillations in the diameter of retinal arterioles in normal persons and in persons with different severity of diabetic retinopathy.

AB - Diabetic retinopathy is characterized by morphological changes in the retina secondary to disturbances in retinal blood flow. Vasomotion is a mechanism for regulating blood flow by spontaneous oscillations in the diameter of retinal resistance arterioles, and has been shown to be disturbed outside the eye in diabetic patients. Therefore, the purpose of the present study was to characterize spontaneous oscillations in the diameter of retinal arterioles in normal persons and in persons with different severity of diabetic retinopathy.

KW - Arterioles

KW - Blood Flow Velocity

KW - Blood Pressure

KW - Diabetes Mellitus, Type 2

KW - Diabetic Retinopathy

KW - Exercise

KW - Female

KW - Heart Rate

KW - Homeostasis

KW - Humans

KW - Male

KW - Middle Aged

KW - Regional Blood Flow

KW - Retinal Artery

KW - Vasodilation

KW - Video Recording

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DO - 10.1167/iovs.12-11182

M3 - Journal article

C2 - 23258153

SN - 0146-0404

VL - 54

SP - 636

EP - 640

JO - Investigative Ophthalmology & Visual Science

JF - Investigative Ophthalmology & Visual Science

IS - 1

ER -