Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)

Mette Norman Erichsen; Tri Hien Viet Huynh; Bjarke Abrahamsen; Jesper Frank Bastlund; Christoffer Bundgaard; Olja Monrad; Anders Bekker-Jensen; Christina Wøhlk Nielsen; Karla Andrea Frydenvang; Anders Asbjørn Jensen; Lennart Bunch

doi:10.1021/jm1009154

Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)

Mette Norman Erichsen, Tri Hien Viet Huynh, Bjarke Abrahamsen, Jesper Frank Bastlund, Christoffer Bundgaard, Olja Monrad, Anders Bekker-Jensen, Christina Wøhlk Nielsen, Karla Andrea Frydenvang, Anders Asbjørn Jensen, Lennart Bunch

Research output: Contribution to journal › Journal article › Research › peer-review

110 Citations (Scopus)

Original language	English
Journal	Journal of Medicinal Chemistry
Volume	53
Issue number	19
Pages (from-to)	7180–7191
ISSN	0022-2623
DOIs	https://doi.org/10.1021/jm1009154
Publication status	Published - 2010

Keywords

Former Faculty of Pharmaceutical Sciences

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10.1021/jm1009154

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Erichsen, M. N., Huynh, T. H. V., Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Monrad, O., Bekker-Jensen, A., Nielsen, C. W., Frydenvang, K. A., Jensen, A. A., & Bunch, L. (2010). Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101). Journal of Medicinal Chemistry, 53(19), 7180–7191. https://doi.org/10.1021/jm1009154

Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1 : 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101). / Erichsen, Mette Norman; Huynh, Tri Hien Viet; Abrahamsen, Bjarke; Bastlund, Jesper Frank; Bundgaard, Christoffer; Monrad, Olja; Bekker-Jensen, Anders; Nielsen, Christina Wøhlk; Frydenvang, Karla Andrea ; Jensen, Anders Asbjørn ; Bunch, Lennart.

In: Journal of Medicinal Chemistry, Vol. 53, No. 19, 2010, p. 7180–7191.

Research output: Contribution to journal › Journal article › Research › peer-review

Erichsen, MN, Huynh, THV, Abrahamsen, B, Bastlund, JF, Bundgaard, C, Monrad, O, Bekker-Jensen, A, Nielsen, CW, Frydenvang, KA , Jensen, AA & Bunch, L 2010, 'Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)', Journal of Medicinal Chemistry, vol. 53, no. 19, pp. 7180–7191. https://doi.org/10.1021/jm1009154

Erichsen MN, Huynh THV, Abrahamsen B, Bastlund JF, Bundgaard C, Monrad O et al. Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101). Journal of Medicinal Chemistry. 2010;53(19):7180–7191. https://doi.org/10.1021/jm1009154

Erichsen, Mette Norman ; Huynh, Tri Hien Viet ; Abrahamsen, Bjarke ; Bastlund, Jesper Frank ; Bundgaard, Christoffer ; Monrad, Olja ; Bekker-Jensen, Anders ; Nielsen, Christina Wøhlk ; Frydenvang, Karla Andrea ; Jensen, Anders Asbjørn ; Bunch, Lennart. / Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1 : 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101). In: Journal of Medicinal Chemistry. 2010 ; Vol. 53, No. 19. pp. 7180–7191.

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