Sucrose counteracts the anti-inflammatory effect of fish oil in adipose tissue and increases obesity development in mice

Tao Ma, Bjørn Liaset, Qin Hao, Rasmus Koefoed Petersen, Even Fjære, Ha Thi Ngo, Haldis Haukås Lillefosse, Stine Ringholm Jørgensen, Si Brask Sonne, Jonas Thue Treebak, Henriette Pilegaard, Livar Frøyland, Karsten Kristiansen, Lise Madsen

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Abstract

Polyunsaturated n-3 fatty acids (n-3 PUFAs) are reported to protect against high fat diet-induced obesity and inflammation in adipose tissue. Here we aimed to investigate if the amount of sucrose in the background diet influences the ability of n-3 PUFAs to protect against diet-induced obesity, adipose tissue inflammation and glucose intolerance.
Original languageEnglish
JournalP L o S One
Volume6
Issue number6
Number of pages12
ISSN1932-6203
DOIs
Publication statusPublished - 2011

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