Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019

Anette M. Hammerum; Ulrik S. Justesen; Mette Pinholt; Louise Roer; Hülya Kaya; Peder Worning; Sanne Nygaard; Michael Kemp; Marianne Engell Clausen; Karen Leth Nielsen; Jurgita Samulioniené; Mona Kjærsgaard; Claus Østergaard; John Coia; Turid Snekloth Søndergaard; Shahin Gaini; Kristian Schønning; Henrik Westh; Henrik Hasman; Barbara Juliane Holzknecht

doi:10.2807/1560-7917.ES.2019.24.34.1900503

Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019

Anette M. Hammerum, Ulrik S. Justesen, Mette Pinholt, Louise Roer, Hülya Kaya, Peder Worning, Sanne Nygaard, Michael Kemp, Marianne Engell Clausen, Karen Leth Nielsen, Jurgita Samulioniené, Mona Kjærsgaard, Claus Østergaard, John Coia, Turid Snekloth Søndergaard, Shahin Gaini, Kristian Schønning, Henrik Westh, Henrik Hasman, Barbara Juliane Holzknecht

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type.

Original language	English
Journal	Eurosurveillance
Volume	24
Issue number	34
Pages (from-to)	1-5
ISSN	1025-496X
DOIs	https://doi.org/10.2807/1560-7917.ES.2019.24.34.1900503
Publication status	Published - 2019

Keywords

Enterococci
MLST
vanA
vanB
VRE
VVE

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10.2807/1560-7917.ES.2019.24.34.1900503Licence: CC BY

eurosurv-24-34-1Final published version, 400 KBLicence: CC BY

Cite this

Hammerum, A. M., Justesen, U. S., Pinholt, M., Roer, L., Kaya, H., Worning, P., Nygaard, S., Kemp, M., Clausen, M. E., Nielsen, K. L., Samulioniené, J., Kjærsgaard, M., Østergaard, C., Coia, J., Søndergaard, T. S., Gaini, S., Schønning, K., Westh, H., Hasman, H., & Holzknecht, B. J. (2019). Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019. Eurosurveillance, 24(34), 1-5. https://doi.org/10.2807/1560-7917.ES.2019.24.34.1900503

Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019. / Hammerum, Anette M.; Justesen, Ulrik S.; Pinholt, Mette; Roer, Louise; Kaya, Hülya; Worning, Peder; Nygaard, Sanne; Kemp, Michael; Clausen, Marianne Engell; Nielsen, Karen Leth; Samulioniené, Jurgita; Kjærsgaard, Mona; Østergaard, Claus; Coia, John; Søndergaard, Turid Snekloth; Gaini, Shahin; Schønning, Kristian ; Westh, Henrik; Hasman, Henrik; Holzknecht, Barbara Juliane.

In: Eurosurveillance, Vol. 24, No. 34, 2019, p. 1-5.

Research output: Contribution to journal › Journal article › Research › peer-review

Hammerum, AM, Justesen, US, Pinholt, M, Roer, L, Kaya, H, Worning, P, Nygaard, S, Kemp, M, Clausen, ME, Nielsen, KL, Samulioniené, J, Kjærsgaard, M, Østergaard, C, Coia, J, Søndergaard, TS, Gaini, S, Schønning, K , Westh, H, Hasman, H & Holzknecht, BJ 2019, 'Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019', Eurosurveillance, vol. 24, no. 34, pp. 1-5. https://doi.org/10.2807/1560-7917.ES.2019.24.34.1900503

Hammerum, Anette M. ; Justesen, Ulrik S. ; Pinholt, Mette ; Roer, Louise ; Kaya, Hülya ; Worning, Peder ; Nygaard, Sanne ; Kemp, Michael ; Clausen, Marianne Engell ; Nielsen, Karen Leth ; Samulioniené, Jurgita ; Kjærsgaard, Mona ; Østergaard, Claus ; Coia, John ; Søndergaard, Turid Snekloth ; Gaini, Shahin ; Schønning, Kristian ; Westh, Henrik ; Hasman, Henrik ; Holzknecht, Barbara Juliane. / Surveillance of vancomycin-resistant enterococci reveals shift in dominating clones and national spread of a vancomycin-variable vanA Enterococcus faecium ST1421-CT1134 clone, Denmark, 2015 to March 2019. In: Eurosurveillance. 2019 ; Vol. 24, No. 34. pp. 1-5.

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abstract = "We describe clonal shifts in vanA Enterococcus faecium isolates from clinical samples obtained from patients in Denmark from 2015 to the first quarter (Q1) of 2019. During Q1 2019, the vancomycin-variable enterococci (VVE) ST1421-CT1134 vanA E. faecium became the most dominant vanA E. faecium clone and has spread to all five regions in Denmark. Among 174 E. faecium isolates with vanA, vanB or vanA/vanB genes in Q1 2019, 44% belonged to this type.",

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