Synthesis and Selective Functionalization of [1,2,4]Triazolo[4,3-a]pyrazines

Charles Sylvain Demmer, Morten Jorgensen, Jan Kehler, Lennart Bunch, Lars K. Rasmussen

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10 Citations (Scopus)

Abstract

A new tactic for the synthesis and selective functionalization of [1,2,4]triazolo[4,3-a]pyrazines has been developed using an oxidative cyclization as key step. Furthermore, novel strategies for introducing diverse substituents in all positions of the heterocycle were identified.
Original languageEnglish
JournalSYNLETT: Accounts and Rapid Communications in Chemical Synthesis
Volume26
Issue number4
Pages (from-to)519-524
Number of pages6
ISSN0936-5214
DOIs
Publication statusPublished - 2015

Keywords

  • heterocyclic chemistry
  • cyclization
  • lithiation
  • cross-coupling
  • PhI(OAc)(2)

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