Synthesis of substituted 2-cyanoarylboronic esters

Morten Lysén; Henriette M Hansen; Mikael Begtrup; Jesper L Kristensen

doi:10.1021/jo052400g

Synthesis of substituted 2-cyanoarylboronic esters

Morten Lysén, Henriette M Hansen, Mikael Begtrup, Jesper L Kristensen

Medicinal Chemistry Research

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Abstract

The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.

Original language	English
Journal	Journal of Organic Chemistry
Volume	71
Issue number	6
Pages (from-to)	2518-20
Number of pages	3
ISSN	0022-3263
DOIs	https://doi.org/10.1021/jo052400g
Publication status	Published - 17 Mar 2006

Keywords

Boronic Acids
Molecular Structure
Stereoisomerism

Access to Document

10.1021/jo052400g

Cite this

@article{864ae1c586b14ba1a2a6776581490a38,

title = "Synthesis of substituted 2-cyanoarylboronic esters",

abstract = "The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.",

keywords = "Boronic Acids, Molecular Structure, Stereoisomerism",

author = "Morten Lys{\'e}n and Hansen, {Henriette M} and Mikael Begtrup and Kristensen, {Jesper L}",

year = "2006",

month = mar,

day = "17",

doi = "10.1021/jo052400g",

language = "English",

volume = "71",

pages = "2518--20",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "6",

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TY - JOUR

T1 - Synthesis of substituted 2-cyanoarylboronic esters

AU - Lysén, Morten

AU - Hansen, Henriette M

AU - Begtrup, Mikael

AU - Kristensen, Jesper L

PY - 2006/3/17

Y1 - 2006/3/17

N2 - The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.

AB - The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.

KW - Boronic Acids

KW - Molecular Structure

KW - Stereoisomerism

U2 - 10.1021/jo052400g

DO - 10.1021/jo052400g

M3 - Journal article

C2 - 16526808

VL - 71

SP - 2518

EP - 2520

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

SN - 0022-3263

IS - 6

ER -