T-cell responses in malaria

L Hviid; P H Jakobsen; Y A Abu-Zeid; T G Theander

T-cell responses in malaria

L Hviid, P H Jakobsen, Y A Abu-Zeid, T G Theander

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

Abstract

Malaria is caused by infection with protozoan parasites of the genus Plasmodium. It remains one of the most severe health problems in tropical regions of the world, and the rapid spread of resistance to drugs and insecticides has stimulated intensive research aimed at the development of a malaria vaccine. Despite this, no efficient operative vaccine is currently available. A large amount of information on T-cell responses to malaria antigens has been accumulated, concerning antigens derived from all stages of the parasite life cycle. The present review summarizes some of that information, and discusses factors affecting the responses of T cells to malaria antigens.

Original language	English
Journal	Acta Pathologica Microbiologica et Immunologica Scandinavica
Volume	100
Issue number	2
Pages (from-to)	95-106
Number of pages	11
ISSN	0903-4641
Publication status	Published - 1992

Bibliographical note

Keywords: Amino Acid Sequence; Animals; Antigens, Protozoan; Humans; Immunity, Cellular; Malaria; Malaria, Falciparum; Molecular Sequence Data; T-Lymphocytes

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title = "T-cell responses in malaria",

abstract = "Malaria is caused by infection with protozoan parasites of the genus Plasmodium. It remains one of the most severe health problems in tropical regions of the world, and the rapid spread of resistance to drugs and insecticides has stimulated intensive research aimed at the development of a malaria vaccine. Despite this, no efficient operative vaccine is currently available. A large amount of information on T-cell responses to malaria antigens has been accumulated, concerning antigens derived from all stages of the parasite life cycle. The present review summarizes some of that information, and discusses factors affecting the responses of T cells to malaria antigens.",

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T1 - T-cell responses in malaria

AU - Hviid, L

AU - Jakobsen, P H

AU - Abu-Zeid, Y A

AU - Theander, T G

N1 - Keywords: Amino Acid Sequence; Animals; Antigens, Protozoan; Humans; Immunity, Cellular; Malaria; Malaria, Falciparum; Molecular Sequence Data; T-Lymphocytes

PY - 1992

Y1 - 1992

N2 - Malaria is caused by infection with protozoan parasites of the genus Plasmodium. It remains one of the most severe health problems in tropical regions of the world, and the rapid spread of resistance to drugs and insecticides has stimulated intensive research aimed at the development of a malaria vaccine. Despite this, no efficient operative vaccine is currently available. A large amount of information on T-cell responses to malaria antigens has been accumulated, concerning antigens derived from all stages of the parasite life cycle. The present review summarizes some of that information, and discusses factors affecting the responses of T cells to malaria antigens.

AB - Malaria is caused by infection with protozoan parasites of the genus Plasmodium. It remains one of the most severe health problems in tropical regions of the world, and the rapid spread of resistance to drugs and insecticides has stimulated intensive research aimed at the development of a malaria vaccine. Despite this, no efficient operative vaccine is currently available. A large amount of information on T-cell responses to malaria antigens has been accumulated, concerning antigens derived from all stages of the parasite life cycle. The present review summarizes some of that information, and discusses factors affecting the responses of T cells to malaria antigens.

M3 - Journal article

C2 - 1554496

SN - 0903-4641

VL - 100

SP - 95

EP - 106

JO - Acta Pathologica Microbiologica et Immunologica Scandinavica

JF - Acta Pathologica Microbiologica et Immunologica Scandinavica

IS - 2

ER -